| Gene Symbol |
DRG1
|
| Entrez Gene |
4733
|
| Alt Symbol |
NEDD3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
developmentally regulated GTP binding protein 1
|
| Other Description |
DRG-1|NEDD-3|developmentally regulated GTP-binding protein 1|developmentally-regulated GTP-binding protein 1|neural precursor cell expressed developmentally down-regulated protein 3|neural precursor cell expressed, developmentally down-regulated 3
|
| Swissprots |
Q9UGF2 Q8WW69 Q6FGP8 Q9Y295 B2RDS8
|
| Accessions |
EAW59974 EAW59975 EAW59976 Q9Y295 AF078103 AAD12240 AJ005940 CAA06775 AK098576 AK315659 BAG38025 AL133085 CAB61403 BC019285 AAH19285 BC020803 AAH20803 BT007237 AAP35901 BU584654 CR456488 CAG30374 CR542059 CAG46856 CU013048 CAK54479 CU013336 CAK54778 DQ890690 ABM81616 DQ893872 ABM84798 NM_004147 NP_004138
|
| Function |
Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15676025, ECO:0000269|PubMed:19819225}. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes.
|
| Tissue Specificity |
High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. {ECO:0000269|PubMed:10760581}.
|
![Western Blot: DRG1 Overexpression Lysate (Adult Normal) [NBL1-10020] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DRG1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3613_DRG1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10020-img0002.jpg)