Gene Symbol | DRG1 |
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Entrez Gene | 4733 |
Alt Symbol | NEDD3 |
Species | Human |
Gene Type | protein-coding |
Description | developmentally regulated GTP binding protein 1 |
Other Description | DRG-1|NEDD-3|developmentally regulated GTP-binding protein 1|developmentally-regulated GTP-binding protein 1|neural precursor cell expressed developmentally down-regulated protein 3|neural precursor cell expressed, developmentally down-regulated 3 |
Swissprots | Q9UGF2 Q8WW69 Q6FGP8 Q9Y295 B2RDS8 |
Accessions | EAW59974 EAW59975 EAW59976 Q9Y295 AF078103 AAD12240 AJ005940 CAA06775 AK098576 AK315659 BAG38025 AL133085 CAB61403 BC019285 AAH19285 BC020803 AAH20803 BT007237 AAP35901 BU584654 CR456488 CAG30374 CR542059 CAG46856 CU013048 CAK54479 CU013336 CAK54778 DQ890690 ABM81616 DQ893872 ABM84798 NM_004147 NP_004138 |
Function | Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15676025, ECO:0000269|PubMed:19819225}. Note=The DRG1-DFRP2/ZC3H15 complex associates with polysomes. |
Tissue Specificity | High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. {ECO:0000269|PubMed:10760581}. |
DRG1 CRISPR/Cas9 KO Plasmid (h) - sc-409654 from Santa Cruz Biotechnology
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DRG1 HDR Plasmid (h) - sc-409654-HDR from Santa Cruz Biotechnology
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DRG1 Double Nickase Plasmid (h) - sc-409654-NIC from Santa Cruz Biotechnology
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DRG1 Double Nickase Plasmid (h2) - sc-409654-NIC-2 from Santa Cruz Biotechnology
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DRG1 CRISPR Activation Plasmid (h) - sc-409654-ACT from Santa Cruz Biotechnology
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DRG1 CRISPR Activation Plasmid (h2) - sc-409654-ACT-2 from Santa Cruz Biotechnology
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DRG1 Lentiviral Activation Particles (h) - sc-409654-LAC from Santa Cruz Biotechnology
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DRG1 Lentiviral Activation Particles (h2) - sc-409654-LAC-2 from Santa Cruz Biotechnology
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DRG1 siRNA (h) - sc-62240 from Santa Cruz Biotechnology
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DRG1 shRNA Plasmid (h) - sc-62240-SH from Santa Cruz Biotechnology
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DRG1 shRNA (h) Lentiviral Particles - sc-62240-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU159361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7490 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7490 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01274 from Sigma-Aldrich
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DRG1 siRNA (Human) - CRH3143 from Cohesion Biosciences
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DRG1 - MBS8218859 from MyBioSource
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shRNA set against Human DRG1 (NM_004147.3) - SHH281069 from Creative biogene
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shRNA set against Human DRG1(NM_004147.3) - SHH015887 from Creative biogene
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Human DRG1 siRNA - orb263645 from Biorbyt
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DRG1 shRNA Plasmid (Human) - CHH3143 from Cohesion Biosciences
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DRG1 miRNA 3'UTR clone - MiUTR1H-02996 from Creative biogene
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