| Gene Symbol |
MYT1
|
| Entrez Gene |
4661
|
| Alt Symbol |
C20orf36, MTF1, MYTI, NZF2, PLPB1, ZC2HC4A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myelin transcription factor 1
|
| Other Description |
myelin transcription factor I|neural zinc finger transcription factor 2|proteolipid protein binding protein|proteolipid protein-binding protein
|
| Swissprots |
Q01538 F5H7M8 E1P5H0 O94922 Q9UPV2 Q7Z5W2
|
| Accessions |
EAW75155 EAW75157 EAW75158 Q01538 AB020642 BAA74858 BC018917 BC053638 AAH53638 BC062313 AAH62313 M96980 AAA59897 NM_004535 NP_004526
|
| Function |
Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. {ECO:0000269|PubMed:14962745}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. {ECO:0000269|PubMed:8530187}.
|