Gene Symbol | MYT1 |
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Entrez Gene | 4661 |
Alt Symbol | C20orf36, MTF1, MYTI, NZF2, PLPB1, ZC2HC4A |
Species | Human |
Gene Type | protein-coding |
Description | myelin transcription factor 1 |
Other Description | myelin transcription factor I|neural zinc finger transcription factor 2|proteolipid protein binding protein|proteolipid protein-binding protein |
Swissprots | Q01538 F5H7M8 E1P5H0 O94922 Q9UPV2 Q7Z5W2 |
Accessions | EAW75155 EAW75157 EAW75158 Q01538 AB020642 BAA74858 BC018917 BC053638 AAH53638 BC062313 AAH62313 M96980 AAA59897 NM_004535 NP_004526 |
Function | Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription. {ECO:0000269|PubMed:14962745}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Mostly in developing nervous system. Expressed in neural progenitors and oligodendrocyte lineage cells. More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes. {ECO:0000269|PubMed:8530187}. |
MYT1 CRISPR/Cas9 KO Plasmid (h) - sc-407637 from Santa Cruz Biotechnology
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MYT1 HDR Plasmid (h) - sc-407637-HDR from Santa Cruz Biotechnology
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MYT1 Double Nickase Plasmid (h) - sc-407637-NIC from Santa Cruz Biotechnology
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MYT1 Double Nickase Plasmid (h2) - sc-407637-NIC-2 from Santa Cruz Biotechnology
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MYT1 CRISPR Activation Plasmid (h) - sc-407637-ACT from Santa Cruz Biotechnology
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MYT1 CRISPR Activation Plasmid (h2) - sc-407637-ACT-2 from Santa Cruz Biotechnology
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MYT1 Lentiviral Activation Particles (h) - sc-407637-LAC from Santa Cruz Biotechnology
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MYT1 Lentiviral Activation Particles (h2) - sc-407637-LAC-2 from Santa Cruz Biotechnology
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MYT1 siRNA (h) - sc-75858 from Santa Cruz Biotechnology
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MYT1 shRNA Plasmid (h) - sc-75858-SH from Santa Cruz Biotechnology
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MYT1 shRNA (h) Lentiviral Particles - sc-75858-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN14889 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14889 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13182 from Sigma-Aldrich
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MYT1 siRNA (Human) - CRH3081 from Cohesion Biosciences
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shRNA set against Human MYT1 (NM_004535.2) - SHH348576 from Creative biogene
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MYT1 shRNA Plasmid (Human) - CHH3081 from Cohesion Biosciences
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MYT1 miRNA 3'UTR clone - MiUTR1H-06611 from Creative biogene
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