| Gene Symbol |
RUFY1
|
| Entrez Gene |
80230
|
| Alt Symbol |
RABIP4, ZFYVE12
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RUN and FYVE domain containing 1
|
| Other Description |
FYVE-finger protein EIP1|RUN and FYVE domain-containing protein 1|la-binding protein 1|rab4-interacting protein|zinc finger FYVE domain-containing protein 12
|
| Swissprots |
Q96T51 Q71S93 Q9H6I3 Q59FF3
|
| Accessions |
EAW53810 Q96T51 AB209507 BAD92744 AF312367 AAQ14554 AF361055 AAK50771 AK025904 BAB15276 AK075021 AK093848 BAG52773 AK291926 BAF84615 BC016564 BC032571 AAH32571 BP358497 BQ014374 BQ014980 CB988835 DA648204 DA811890 DA925727 JF432721 ADZ15938 XM_005265993 XP_005266050 XM_006714921 XP_006714984 XM_006714922 XP_006714985 XM_011534658 XP_011532960 XM_011534659 XP_011532961 XR_245276 XR_245277 NM_001040451 NP_001035541 NM_001040452 NP_001035542 NM_025158 NP_079434
|
| Function |
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. {ECO:0000269|PubMed:14617813}.
|
| Subcellular Location |
Cytoplasm. Early endosome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Broadly expressed, with highest levels in lung, testis, kidney and brain. {ECO:0000269|PubMed:11877430}.
|
| Top Pathways |
Endocytosis
|