Gene Symbol | RUFY1 |
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Entrez Gene | 80230 |
Alt Symbol | RABIP4, ZFYVE12 |
Species | Human |
Gene Type | protein-coding |
Description | RUN and FYVE domain containing 1 |
Other Description | FYVE-finger protein EIP1|RUN and FYVE domain-containing protein 1|la-binding protein 1|rab4-interacting protein|zinc finger FYVE domain-containing protein 12 |
Swissprots | Q96T51 Q71S93 Q9H6I3 Q59FF3 |
Accessions | EAW53810 Q96T51 AB209507 BAD92744 AF312367 AAQ14554 AF361055 AAK50771 AK025904 BAB15276 AK075021 AK093848 BAG52773 AK291926 BAF84615 BC016564 BC032571 AAH32571 BP358497 BQ014374 BQ014980 CB988835 DA648204 DA811890 DA925727 JF432721 ADZ15938 XM_005265993 XP_005266050 XM_006714921 XP_006714984 XM_006714922 XP_006714985 XM_011534658 XP_011532960 XM_011534659 XP_011532961 XR_245276 XR_245277 NM_001040451 NP_001035541 NM_001040452 NP_001035542 NM_025158 NP_079434 |
Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. {ECO:0000269|PubMed:14617813}. |
Subcellular Location | Cytoplasm. Early endosome membrane; Peripheral membrane protein. |
Tissue Specificity | Broadly expressed, with highest levels in lung, testis, kidney and brain. {ECO:0000269|PubMed:11877430}. |
Top Pathways | Endocytosis |
RUFY1 CRISPR/Cas9 KO Plasmid (h) - sc-409446 from Santa Cruz Biotechnology
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RUFY1 HDR Plasmid (h) - sc-409446-HDR from Santa Cruz Biotechnology
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RUFY1 Double Nickase Plasmid (h) - sc-409446-NIC from Santa Cruz Biotechnology
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RUFY1 Double Nickase Plasmid (h2) - sc-409446-NIC-2 from Santa Cruz Biotechnology
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RUFY1 CRISPR Activation Plasmid (h) - sc-409446-ACT from Santa Cruz Biotechnology
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RUFY1 CRISPR Activation Plasmid (h2) - sc-409446-ACT-2 from Santa Cruz Biotechnology
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RUFY1 Lentiviral Activation Particles (h) - sc-409446-LAC from Santa Cruz Biotechnology
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RUFY1 Lentiviral Activation Particles (h2) - sc-409446-LAC-2 from Santa Cruz Biotechnology
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RUFY1 siRNA (h) - sc-91860 from Santa Cruz Biotechnology
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RUFY1 shRNA Plasmid (h) - sc-91860-SH from Santa Cruz Biotechnology
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RUFY1 shRNA (h) Lentiviral Particles - sc-91860-V from Santa Cruz Biotechnology
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RUFY1 RNAi - H00080230-R01 from Novus Biologicals
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MISSION® esiRNA - EHU070331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18747 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18747 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04389 from Sigma-Aldrich
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RUFY1 siRNA (Human) - CRJ2817 from Cohesion Biosciences
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RUFY1 - MBS8234920 from MyBioSource
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shRNA set against Human RUFY1 (NM_025158.4) - SHH400664 from Creative biogene
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RUFY1 shRNA Plasmid (Human) - CHJ2817 from Cohesion Biosciences
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RUFY1 miRNA 3'UTR clone - MiUTR3H-11156 from Creative biogene
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RUFY1 miRNA 3'UTR clone - MiUTR3H-11157 from Creative biogene
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RUFY1 miRNA 3'UTR clone - MiUTR3H-11158 from Creative biogene
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