| Gene Symbol |
PSMC6
|
| Entrez Gene |
5706
|
| Alt Symbol |
CADP44, HEL-S-73, P44, SUG2, p42
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) 26S subunit, ATPase, 6
|
| Other Description |
26S protease regulatory subunit 10B|26S protease regulatory subunit S10B|26S proteasome AAA-ATPase subunit RPT4|conserved ATPase domain protein 44|epididymis secretory protein Li 73|proteasome 26S subunit ATPase 6|proteasome subunit p42
|
| Swissprots |
B2R975 Q92524 P62333 Q6IBU3 P49719
|
| Accessions |
CAH05701 EAW65645 P62333 AA846884 AF006305 AAB61616 AK127456 AK299155 BAG61203 AK307087 AK313670 BAG36422 BC005390 AAH05390 BM788029 BP384173 BT006843 AAP35489 CR456709 CAG32990 D78275 BAA11338 DQ893704 ABM84630 FJ224299 ACI45991 XR_245706 XR_943495 NM_002806 NP_002797
|
| Function |
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
| Top Pathways |
Proteasome, Epstein-Barr virus infection
|
![Western Blot: PSMC6 Overexpression Lysate (Adult Normal) [NBL1-14893] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PSMC6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3619_PSMC6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14893-img0002.jpg)