Gene Symbol | PSMC6 |
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Entrez Gene | 5706 |
Alt Symbol | CADP44, HEL-S-73, P44, SUG2, p42 |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
Other Description | 26S protease regulatory subunit 10B|26S protease regulatory subunit S10B|26S proteasome AAA-ATPase subunit RPT4|conserved ATPase domain protein 44|epididymis secretory protein Li 73|proteasome 26S subunit ATPase 6|proteasome subunit p42 |
Swissprots | B2R975 Q92524 P62333 Q6IBU3 P49719 |
Accessions | CAH05701 EAW65645 P62333 AA846884 AF006305 AAB61616 AK127456 AK299155 BAG61203 AK307087 AK313670 BAG36422 BC005390 AAH05390 BM788029 BP384173 BT006843 AAP35489 CR456709 CAG32990 D78275 BAA11338 DQ893704 ABM84630 FJ224299 ACI45991 XR_245706 XR_943495 NM_002806 NP_002797 |
Function | The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Proteasome, Epstein-Barr virus infection |
PSMC6 CRISPR/Cas9 KO Plasmid (h) - sc-406272 from Santa Cruz Biotechnology
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PSMC6 HDR Plasmid (h) - sc-406272-HDR from Santa Cruz Biotechnology
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PSMC6 Double Nickase Plasmid (h) - sc-406272-NIC from Santa Cruz Biotechnology
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PSMC6 Double Nickase Plasmid (h2) - sc-406272-NIC-2 from Santa Cruz Biotechnology
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PSMC6 CRISPR Activation Plasmid (h) - sc-406272-ACT from Santa Cruz Biotechnology
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PSMC6 CRISPR Activation Plasmid (h2) - sc-406272-ACT-2 from Santa Cruz Biotechnology
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PSMC6 Lentiviral Activation Particles (h) - sc-406272-LAC from Santa Cruz Biotechnology
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PSMC6 Lentiviral Activation Particles (h2) - sc-406272-LAC-2 from Santa Cruz Biotechnology
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PSMC6 siRNA (h) - sc-92282 from Santa Cruz Biotechnology
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PSMC6 shRNA Plasmid (h) - sc-92282-SH from Santa Cruz Biotechnology
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PSMC6 shRNA (h) Lentiviral Particles - sc-92282-V from Santa Cruz Biotechnology
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PSMC6 RNAi - H00005706-R01V from Novus Biologicals
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PSMC6 RNAi - H00005706-R02 from Novus Biologicals
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MISSION® esiRNA - EHU104831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17613 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17613 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03271 from Sigma-Aldrich
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PSMC6 siRNA (Human) - CRH3852 from Cohesion Biosciences
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shRNA set against Human PSMC6 (NM_002806.3) - SHH385336 from Creative biogene
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PSMC6 shRNA Plasmid (Human) - CHH3852 from Cohesion Biosciences
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PSMC6 miRNA 3'UTR clone - MiUTR3H-05250 from Creative biogene
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