ATP5C1

Gene Symbol	ATP5C1
Entrez Gene	509
Alt Symbol	ATP5C, ATP5CL1
Species	Human
Gene Type	protein-coding
Description	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Other Description	ATP synthase gamma chain, mitochondrial|ATP synthase subunit gamma, mitochondrial|F-ATPase gamma subunit|mitochondrial ATP synthase, gamma subunit 1
Swissprots	Q6I9V2 Q5VYP3 P36542 A8KA31 Q96AS8
Accessions	BAA03994 BAA03995 EAW86372 EAW86373 P36542 AK292896 BAF85585 AK294061 BAG57407 AK296803 BAG59376 BC000470 AAH00470 BC000931 AAH00931 BC010380 BC013394 AAH13394 BC013865 BC016812 AAH16812 BC020824 AAH20824 BC026049 AAH26049 BQ893894 CR457403 CAG33684 D16562 BAA03996 D16563 BAA03997 HQ448142 ADQ32623 XM_011519490 XP_011517792 NM_001001973 NP_001001973 NM_005174 NP_005165
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular Location	Mitochondrion. Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Isoform Heart is expressed specifically in the heart and skeletal muscle, which require rapid energy supply. Isoform Liver is expressed in the brain, liver and kidney. Isoform Heart and Isoform Liver are expressed in the skin, intestine, stomach and aorta.
Top Pathways	Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ATP5C1 (K-17) - sc-241859 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

ATP5C1 (S-19) - sc-241858 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-ATPG antibody - ab154217 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ATPG antibody - ab95095 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATPG antibody - ab74807 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATPG antibody [2A1AA11] (HRP) - ab198407 from Abcam Prices $425.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2A1AA11

Anti-ATP5C1 Antibody (Asp165) - LS-C192078 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76, FITC) - LS-C251995 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76, APC) - LS-C251993 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76, Azide-free, HRP) - LS-C251996 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76, AP) - LS-C251992 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76, PE) - LS-C251997 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76) - LS-C319691 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa131-180) - LS-C119752 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (aa27-40) - LS-C305860 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ATP5C1 Antibody (aa272-286) - LS-C305863 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-ATP5C1 Antibody (aa46-76) - LS-C156654 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 Antibody (clone 2H6) - LS-C337053 from LifeSpan Bioscience Prices $350.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2H6

Anti-ATP5C1 Antibody (aa46-76, Biotin) - LS-C251994 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

ATPG Antibody - NBP2-15525 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ATPG Antibody - NBP2-34138 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-ATP5C1 antibody produced in rabbit - SAB2700096 from Sigma-Aldrich Prices $326.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-ATP5C1 (N-TERM) antibody produced in rabbit - SAB1301237 from Sigma-Aldrich Prices $326.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-ATP5C1 antibody produced in rabbit - HPA060949 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ATPG Antibody - N-terminal region (ARP75941_P050) - ARP75941_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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