Gene Symbol | TMPRSS3 |
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Entrez Gene | 64699 |
Alt Symbol | DFNB10, DFNB8, ECHOS1, TADG12 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protease, serine 3 |
Other Description | serine protease TADG-12|transmembrane protease serine 3|tumor-associated differentially-expressed gene 12 protein |
Swissprots | Q6ZMC3 P57727 Q5USC7 D3DSJ6 |
Accessions | EAX09564 EAX09565 EAX09566 EAX09567 EAX09568 P57727 AB038157 BAB20077 AB038158 BAB20078 AB038159 BAB20079 AB038160 BAB20080 AF201380 AAG37012 AF267741 AAL56664 AI251446 AK131212 AK172842 BAD18806 AY358458 AAQ88823 AY633572 AAT66641 BC074846 AAH74846 BC074847 AAH74847 DA643571 DB217517 NM_001256317 NP_001243246 NM_024022 NP_076927 NM_032404 NP_115780 NM_032405 NP_115781 NR_046020 NM_032401 |
Function | Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro). {ECO:0000250, ECO:0000269|PubMed:12393794}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12393794}; Single-pass type II membrane protein {ECO:0000269|PubMed:12393794}. |
Tissue Specificity | Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas. |
TMPRSS3 (H-100) - sc-368372 from Santa Cruz Biotechnology
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TMPRSS3 (N-16) - sc-19690 from Santa Cruz Biotechnology
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TMPRSS3 (S-15) - sc-19692 from Santa Cruz Biotechnology
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Anti-TMPRSS3 antibody - ab137181 from Abcam
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Anti-TMPRSS3 antibody - ab65947 from Abcam
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Anti-TMPRSS3 antibody - ab56113 from Abcam
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Anti-TMPRSS3 antibody - ab56114 from Abcam
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Anti-TMPRSS3 antibody - ab56116 from Abcam
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Anti-TMPRSS3 antibody - ab57566 from Abcam
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Anti-TMPRSS3 antibody [E7] - ab180047 from Abcam
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Anti-TMPRSS3 antibody [EPR7048] - ab167160 from Abcam
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Anti-TMPRSS3 antibody - C-terminal - ab192763 from Abcam
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Anti-TMPRSS3 antibody - C-terminal - ab171070 from Abcam
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Anti-TMPRSS3 Antibody (N-Terminus) IHC-plus⢠- LS-B11966 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody - LS-C144633 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody - LS-C144634 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody - LS-C153583 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal, AP) - LS-C220928 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal, APC) - LS-C220929 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal, Biotin) - LS-C220930 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal, Azide-free, HRP) - LS-C220933 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal, FITC) - LS-C220931 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal, PE) - LS-C220935 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (Internal) - LS-C328937 from LifeSpan Bioscience
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Anti-TMPRSS3 Antibody (N-Terminus) - LS-C116733 from LifeSpan Bioscience
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