| Gene Symbol |
TMPRSS11A
|
| Entrez Gene |
339967
|
| Alt Symbol |
ECRG1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protease, serine 11A
|
| Other Description |
airway trypsin-like protease 1|epidermal type II transmembrane serine protease|epidermal type-II transmembrane serine protease|esophageal cancer-susceptibility gene 1 protein|transmembrane protease serine 11A
|
| Swissprots |
Q6ZMR5 J3KNQ8 Q2NKI9 Q7RTY4 Q6JE90 Q86TK8
|
| Accessions |
EAX05560 Q6ZMR5 AF071882 AAD41463 AK131518 BAD18660 AK292950 BAF85639 AY498712 AAS78642 BC111796 AAI11797 BN000133 CAD67985 NM_001114387 NP_001107859 NM_182606 NP_872412
|
| Function |
Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers. {ECO:0000269|PubMed:10920976}.
|
