Gene Symbol | TMPRSS11A |
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Entrez Gene | 339967 |
Alt Symbol | ECRG1 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protease, serine 11A |
Other Description | airway trypsin-like protease 1|epidermal type II transmembrane serine protease|epidermal type-II transmembrane serine protease|esophageal cancer-susceptibility gene 1 protein|transmembrane protease serine 11A |
Swissprots | Q6ZMR5 J3KNQ8 Q2NKI9 Q7RTY4 Q6JE90 Q86TK8 |
Accessions | EAX05560 Q6ZMR5 AF071882 AAD41463 AK131518 BAD18660 AK292950 BAF85639 AY498712 AAS78642 BC111796 AAI11797 BN000133 CAD67985 NM_001114387 NP_001107859 NM_182606 NP_872412 |
Function | Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers. {ECO:0000269|PubMed:10920976}. |
TMPRSS11A CRISPR/Cas9 KO Plasmid (h) - sc-415530 from Santa Cruz Biotechnology
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TMPRSS11A HDR Plasmid (h) - sc-415530-HDR from Santa Cruz Biotechnology
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TMPRSS11A Double Nickase Plasmid (h) - sc-415530-NIC from Santa Cruz Biotechnology
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TMPRSS11A Double Nickase Plasmid (h2) - sc-415530-NIC-2 from Santa Cruz Biotechnology
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TMPRSS11A CRISPR Activation Plasmid (h) - sc-415530-ACT from Santa Cruz Biotechnology
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TMPRSS11A CRISPR Activation Plasmid (h2) - sc-415530-ACT-2 from Santa Cruz Biotechnology
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TMPRSS11A Lentiviral Activation Particles (h) - sc-415530-LAC from Santa Cruz Biotechnology
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TMPRSS11A Lentiviral Activation Particles (h2) - sc-415530-LAC-2 from Santa Cruz Biotechnology
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TMPRSS11A siRNA (h) - sc-89126 from Santa Cruz Biotechnology
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TMPRSS11A shRNA Plasmid (h) - sc-89126-SH from Santa Cruz Biotechnology
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TMPRSS11A shRNA (h) Lentiviral Particles - sc-89126-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21702 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21702 from Sigma-Aldrich
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TMPRSS11A siRNA (Human) - CRJ7318 from Cohesion Biosciences
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TMPRSS11A - MBS8237949 from MyBioSource
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shRNA set against Human TMPRSS11A (NM_182606.3) - SHH431368 from Creative biogene
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shRNA set against Human TMPRSS11A(NM_182606.3) - SHL082602 from Creative biogene
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TMPRSS11A shRNA Plasmid (Human) - CHJ7318 from Cohesion Biosciences
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TMPRSS11A miRNA 3'UTR clone - MiUTR1H-10573 from Creative biogene
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