TBL1X

Gene Symbol TBL1X
Entrez Gene 6907
Alt Symbol EBI, SMAP55, TBL1
Species Human
Gene Type protein-coding
Description transducin (beta)-like 1X-linked
Other Description F-box-like/WD repeat-containing protein TBL1X|transducin beta-like protein 1X|transducin-beta-like protein 1, X-linked
Swissprots A8K044 Q86UY2 O60907 A8K4J7
Accessions EAW98771 EAW98772 O60907 AB209608 BAD92845 AK289409 BAF82098 AK290962 BAF83651 BC020374 BC029394 BC032708 AAH32708 BC052304 AAH52304 Y12781 CAA73319 XM_011545571 XP_011543873 NM_001139466 NP_001132938 NM_001139467 NP_001132939 NM_001139468 NP_001132940 NM_005647 NP_005638
Function F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. {ECO:0000269|PubMed:14980219}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10330347}.
Top Pathways Wnt signaling pathway

TBL1 (A-3) - sc-137082 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TBL1 (A-3): sc-137082. Western blot analysis of TBL1X expression in non-transfected: sc-117752 (A) and human TBL1X transfected: sc-115235 (B) 293T whole cell lysates.

TBL1 (H-3) - sc-137006 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TBL1 (H-3): sc-137006. Western blot analysis of TBL1 expression in Y79 (A) and HeLa (B) whole cell lysates.

TBL1 (H-11) - sc-137083 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TBL1 (H-11): sc-137083. Western blot analysis of TBL1X expression in non-transfected: sc-117752 (A) and human TBL1X transfected: sc-115235 (B) 293T whole cell lysates.

TBL1X (F-2) - sc-365661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TBL1X (F-2): sc-365661. Western blot analysis of TBL1X expression in HeLa whole cell lysate.

TBL1 (G-17) - sc-34539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TBL1 (H-367) - sc-11391 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TBL1 (H-367): sc-11391. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing nuclear and cytoplasmic staining of glandular cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

TBL1X (T-15) - sc-34536 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TBL1X (T-15): sc-34536. Western blot analysis of TBL1X expression in Y79 nuclear extract.

Anti-TBL1 antibody - ab2243 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TBL1 antibody [4H2-D5-E9] - ab106150 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H2-D5-E9
Anti-TBL1 antibody [4H2-D5-E9] (ab106150) at 1/500 dilution + HeLa cell nuclear extract at 40 µg

Anti-TBL1 antibody - ChIP Grade - ab24548 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TBL1 antibody - ChIP Grade (ab24548) at 1/1000 dilution + HeLa nuclear extract.

Anti-TBL1X / TBL1 Antibody (clone GF1) - LS-C190312 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-TBL1X / TBL1 Antibody (C-Terminus) - LS-C20219 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Staining (4 ug/ml) of Human Brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Anti-TBL1X / TBL1 Antibody (clone 2B6) - LS-C133468 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B6
Immunoperoxidase of monoclonal antibody to TBL1X on formalin-fixed paraffin-embedded human cerebral cortex. [antibody concentration 1.5 ug/ml]

TBL1 Antibody (2B6) - H00006907-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B6
Immunohistochemistry-Paraffin: TBL1 Antibody (2B6) [H00006907-M07] - Analysis of monoclonal antibody to TBL1X on formalin-fixed paraffin-embedded human cerebral cortex. Antibody concentration 1.5 ug/ml

TBL1 Antibody - NB300-872 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: TBL1 Antibody [NB300-872] - staining (4ug/ml) of Human Brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

TBL1 Antibody - NBP1-31058 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TBL1 Antibody [NBP1-31058] - Sample(30 ug of whole cell lysate)A:HeLa S3 7. 5% SDS PAGE, antibody diluted at 1:1000.

TBL1 Antibody - H00006907-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: TBL1 Antibody [H00006907-A01] - TBL1X polyclonal antibody (A01), Lot # 051109JC01 Western Blot analysis of TBL1X expression in 293 ( Cat # L026V1 ).

TBL1 Antibody - H00006907-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: TBL1 Antibody [H00006907-B01P] - Analysis of TBL1X expression in transfected 293T cell line by TBL1X polyclonal antibody. Lane 1: TBL1X transfected lysate(57.86 KDa). Lane 2: Non-transfected lysate.

TBL1 Antibody - H00006907-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TBL1 Antibody [H00006907-D01P] - Analysis of TBL1X expression in transfected 293T cell line by TBL1X polyclonal antibody.Lane 1: TBL1X transfected lysate(57.00 KDa).Lane 2: Non-transfected lysate.

TBL1 Antibody - H00006907-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TBL1 Polyclonal Antibody - bs-4219R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-TBL1X Polyclonal Antibody, Unconjugated (bs-4219R)at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-Transducin β antibody produced in rabbit - T2075 from Sigma-Aldrich

Prices $403.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TBL1X antibody produced in mouse - SAB1409723 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-TBL1X: <B>Cat. No. SAB1409723</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Monoclonal Anti-TBL1X antibody produced in mouse - WH0006907M7 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B6
<B>Sandwich ELISA</B><BR/>Monoclonal Anti-TBL1X, <B>Cat. No. WH0006907M7</B>: the detection limit for recombinant GST tagged TBL1X is approximately 0.3ng/mL.

Anti-TBL1X antibody produced in rabbit - SAB1411330 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TBL1X: <B>Cat. No. SAB1411330</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~57 kDa using TBL1X transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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