SEC61A1

Gene Symbol SEC61A1
Entrez Gene 29927
Alt Symbol HSEC61, SEC61, SEC61A
Species Human
Gene Type protein-coding
Description Sec61 alpha 1 subunit (S. cerevisiae)
Other Description Sec61 alpha-1|protein transport protein SEC61 alpha subunit|protein transport protein Sec61 subunit alpha|protein transport protein Sec61 subunit alpha isoform 1|sec61 homolog
Swissprots Q5JPF8 Q8NC71 Q8N0Z4 P61619 Q9BU16 Q8N3U3 Q9Y2R3
Accessions CAF86948 EAW79324 EAW79325 EAW79326 EAW79327 P61619 AF077032 AAD27765 AF084458 AAD39847 AF346602 AAK29083 AK001689 BAG50960 AK027423 BAG51318 AK027452 BAG51323 AK027454 BAG51324 AK027458 BAG51326 AK074706 BAG51989 AK074907 BAC11283 AK074928 BAC11298 AK075148 BAC11434 AK129816 AK297239 BAG59720 AK299118 BAG61173 AL831940 CAD38592 AL832821 CAI46127 BC002951 BC029970 BC152927 AAI52928 BC156688 AAI56689 NM_013336 NP_037468
Function Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways Protein export, Vibrio cholerae infection, Phagosome, Protein processing in endoplasmic reticulum

Sec61α (G-20) - sc-12322 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Sec61α (G-20): sc-12322. Western blot analysis of Sec61α2 expression in non-transfected 293T: sc-117752 (A), mouse Sec61α2 transfected 293T: sc-127520 (B) and HeLa (C) whole cell lysates.

Sec61α (G-2) - sc-393182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Sec61 (G-2): sc-393182. Western blot analysis of Sec61 expression in K-562 (A), Ramos (B), HeLa (C), A-431 (D) and HT-1080 (E) whole cell lysates.

Sec61α (H-296) - sc-25553 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SEC61A antibody - ab97537 from Abcam

Prices $0.00
Sizes 50 µl
Host Sheep
Clonality Polyclonal
Anti-SEC61A antibody (ab97537) at 1/1000 dilution + A431 whole cell lysate at 30 µg

Anti-SEC61A antibody [EPR14379] - ab183046 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14379
Western blot analysis of SEC61A in Daudi cell lysate immunoprecipitated using ab183046 at 1/50 dilution (Lane 1). Lane 2: Negative control.Secondary antibody: Anti-Rabbit IgG (HRP) specific to the non-reduced form of IgG at 1/1500 dilution.

Anti-SEC61A1 / SEC61 Antibody (aa463-476) - LS-C26253 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC61A1 / SEC61 Antibody (aa13-31) - LS-C91266 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SEC61A1 / SEC61 Antibody (aa463-476) - LS-C152783 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
WB: Rat brain microsomal preparation was probed with Anti-Sec61

Anti-SEC61A1 / SEC61 Antibody (aa463-476) IHC-plus™ - LS-B5905 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SEC61A1 / SEC61 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5905 concentration 3.75 ug/ml.

Anti-SEC61A1 / SEC61 Antibody (aa378-427) - LS-C151929 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SEC61A1 / SEC61 antibody Western Blot of Human Placenta. Antibody Dilution: 1.0ug/ml. Antibody dilution: 1 ug/ml.

Anti-SEC61A1 / SEC61 Antibody (aa413-476) - LS-C185813 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Cal27 xenograft using SEC61A1 antibody at 1:500 dilution.

SEC61A Antibody - NBP1-31267 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SEC61A Antibody - NBP2-33437 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SEC61A Antibody [NBP2-33437] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue

SEC61A Antibody - NB100-768 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SEC61A Antibody [NB100-768] - Analysis of SEC61A in Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer) using this antibody at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SEC61A1 antibody produced in rabbit - HPA045070 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SEC61A1: <B>Cat. No. HPA045070</B>: Immunohistochemical staining of Human testis shows strong cytoplasmic and nuclear positivity in Leydig cells.

Anti-SEC61A1 antibody produced in rabbit - SAB2700328 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SEC61A1: <B>Cat. No. SAB2700328</B>: Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using SEC61A1 antibody at 1:500 dilution.

Anti-SEC61A1 antibody produced in goat - SAB2500917 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SEC61A1: <B>Cat. No. SAB2500917</B>: staining (3 μg/mL) of Daudi lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

SEC61A1 Antibody - C-terminal region (ARP65273_P050) - ARP65273_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SEC61A1-Antibody - AF1965a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1965a (0.3 µg/ml) staining of Human Brain (Cerebellum) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SEC61A1 Antibody (OAEB02238) - OAEB02238 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SEC61A1 antibody - 70R-20146 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

SEC61A1 antibody (OAGA00509) - OAGA00509 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SEC61A1 antibody - 70R-13012 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SEC61A1 antibody - 15512-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human liver using 15512-1-AP(SEC61A1 antibody) at dilution of 1:100 (under 40x lens)

SEC61A1 (C-term) antibody - AP15866PU-N from Acris Antibodies

Prices $310.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer) using SEC61A1 Antibody Cat.-No AP15866PU-N at 0.3 µg/ml. Primary incubation was 1 hour. Detected by chemiluminescence.
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