| Gene Symbol |
SEC61A1
|
| Entrez Gene |
29927
|
| Alt Symbol |
HSEC61, SEC61, SEC61A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Sec61 alpha 1 subunit (S. cerevisiae)
|
| Other Description |
Sec61 alpha-1|protein transport protein SEC61 alpha subunit|protein transport protein Sec61 subunit alpha|protein transport protein Sec61 subunit alpha isoform 1|sec61 homolog
|
| Swissprots |
Q5JPF8 Q8NC71 Q8N0Z4 P61619 Q9BU16 Q8N3U3 Q9Y2R3
|
| Accessions |
CAF86948 EAW79324 EAW79325 EAW79326 EAW79327 P61619 AF077032 AAD27765 AF084458 AAD39847 AF346602 AAK29083 AK001689 BAG50960 AK027423 BAG51318 AK027452 BAG51323 AK027454 BAG51324 AK027458 BAG51326 AK074706 BAG51989 AK074907 BAC11283 AK074928 BAC11298 AK075148 BAC11434 AK129816 AK297239 BAG59720 AK299118 BAG61173 AL831940 CAD38592 AL832821 CAI46127 BC002951 BC029970 BC152927 AAI52928 BC156688 AAI56689 NM_013336 NP_037468
|
| Function |
Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane- bound ribosomes, either directly or through adapter proteins.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Top Pathways |
Protein export, Vibrio cholerae infection, Phagosome, Protein processing in endoplasmic reticulum
|