| Gene Symbol |
Rad51ap1
|
| Entrez Gene |
19362
|
| Alt Symbol |
2510006L10Rik, RAB22
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
RAD51 associated protein 1
|
| Other Description |
RAD51-associated protein 1|RAD51-interacting protein|rad51ap1
|
| Swissprots |
Q99L94 O55219 Q9D0J0 Q8BP36 Q8C551
|
| Accessions |
EDK99847 EDK99848 EDK99849 Q8C551 AK010920 AK011379 BAB27579 AK077829 BAC37025 AK079525 BAC37671 AK166703 BC003738 AAH03738 BC022586 BC040809 U93583 AAB91541 XM_006505763 XP_006505826 XR_377433 NM_009013 NP_033039
|
| Function |
May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:9192668}. Note=Colocalizes with RAD51 to multiple nuclear foci.
|
| Tissue Specificity |
Most abundantly expressed in testis. Also expressed in spleen, thymus and bone marrow. Not detected in heart, kidney or liver. {ECO:0000269|PubMed:9192668}.
|