Gene Symbol | Rad51ap1 |
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Entrez Gene | 19362 |
Alt Symbol | 2510006L10Rik, RAB22 |
Species | Mouse |
Gene Type | protein-coding |
Description | RAD51 associated protein 1 |
Other Description | RAD51-associated protein 1|RAD51-interacting protein|rad51ap1 |
Swissprots | Q99L94 O55219 Q9D0J0 Q8BP36 Q8C551 |
Accessions | EDK99847 EDK99848 EDK99849 Q8C551 AK010920 AK011379 BAB27579 AK077829 BAC37025 AK079525 BAC37671 AK166703 BC003738 AAH03738 BC022586 BC040809 U93583 AAB91541 XM_006505763 XP_006505826 XR_377433 NM_009013 NP_033039 |
Function | May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9192668}. Note=Colocalizes with RAD51 to multiple nuclear foci. |
Tissue Specificity | Most abundantly expressed in testis. Also expressed in spleen, thymus and bone marrow. Not detected in heart, kidney or liver. {ECO:0000269|PubMed:9192668}. |
RAD51AP1 CRISPR/Cas9 KO Plasmid (m) - sc-422582 from Santa Cruz Biotechnology
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RAD51AP1 HDR Plasmid (m) - sc-422582-HDR from Santa Cruz Biotechnology
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RAD51AP1 Double Nickase Plasmid (m) - sc-422582-NIC from Santa Cruz Biotechnology
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RAD51AP1 Double Nickase Plasmid (m2) - sc-422582-NIC-2 from Santa Cruz Biotechnology
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RAD51AP1 CRISPR Activation Plasmid (m) - sc-422582-ACT from Santa Cruz Biotechnology
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RAD51AP1 CRISPR Activation Plasmid (m2) - sc-422582-ACT-2 from Santa Cruz Biotechnology
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RAD51AP1 Lentiviral Activation Particles (m) - sc-422582-LAC from Santa Cruz Biotechnology
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RAD51AP1 Lentiviral Activation Particles (m2) - sc-422582-LAC-2 from Santa Cruz Biotechnology
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RAD51AP1 siRNA (m) - sc-152676 from Santa Cruz Biotechnology
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RAD51AP1 shRNA Plasmid (m) - sc-152676-SH from Santa Cruz Biotechnology
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RAD51AP1 shRNA (m) Lentiviral Particles - sc-152676-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU060231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN39831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND39831 from Sigma-Aldrich
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RAD51AP1 siRNA (Mouse) - CRM3390 from Cohesion Biosciences
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RAD51AP1 - MBS8224542 from MyBioSource
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shRNA set against Mouse RAD51AP1 (NM_009013.3) - SHH389012 from Creative biogene
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shRNA set against Mouse Rad51ap1(NM_009013.3) - SHR161806 from Creative biogene
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RAD51AP1 shRNA Plasmid (Mouse) - CHM3390 from Cohesion Biosciences
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RAD51AP1 miRNA 3'UTR clone - MiUTR1M-09887 from Creative biogene
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