Gene Symbol | HTA1 |
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Entrez Gene | 851811 |
Alt Symbol | H2A1, SPT11 |
Species | Yeast |
Gene Type | protein-coding |
Description | histone H2A |
Other Description | - |
Swissprots | D6VSK7 P04911 |
Accessions | DAA12067 P04911 NM_001180533 NP_010511 |
Function | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. {ECO:0000269|PubMed:11140636, ECO:0000269|PubMed:15458641, ECO:0000269|PubMed:15610741, ECO:0000269|PubMed:16299494}. |
Subcellular Location | Nucleus. Chromosome. |
Anti-Histone H2A (phospho S129) antibody [EPR17588] - ChIP Grade - ab181447 from Abcam
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Anti-Histone H2A (phospho S129) antibody - ChIP Grade - ab15083 from Abcam
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Anti-Histone H2A (yeast) (phospho S129) antibody - ab17353 from Abcam
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Anti-phospho Histone H2A (Ser129) Antibody - 07-745-I from EMD Millipore
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