LRPPRC

Gene Symbol LRPPRC
Entrez Gene 10128
Alt Symbol CLONE-23970, GP130, LRP130, LSFC
Species Human
Gene Type protein-coding
Description leucine-rich pentatricopeptide repeat containing
Other Description 130 kDa leucine-rich protein|LRP 130|leucine-rich PPR motif-containing protein, mitochondrial|leucine-rich PPR-motif containing|mitochondrial leucine-rich PPR motif-containing protein
Swissprots Q6ZUD8 Q7Z7A6 A0PJE3 A8K1V1 Q53PC0 Q96D84 P42704 Q53QN7
Accessions AAY24012 AAY24043 ADP90894 ADP90895 ADP90896 ADP90897 ADP90898 ADP90899 ADP90900 ADP90901 ADP90902 ADP90903 ADP90904 ADP90905 ADP90906 ADP90907 ADP90908 ADP90909 ADP90910 ADP90911 ADP90912 ADP90913 ADP90914 ADP90915 ADP90916 ADP90917 ADP90918 ADP90919 ADP90920 ADP90921 ADP90922 ADP90923 ADP90924 ADP90925 ADP90926 ADP90927 ADP90928 ADP90929 ADP90930 ADP90931 ADP90932 ADP90933 EAX00284 P42704 AF052133 AK125781 BAC86287 AK130686 AK290016 BAF82705 AK299869 BAG61722 AK308348 AY289212 AAP41922 BC010282 AAH10282 BC026034 AAH26034 BC038181 BC050311 AAH50311 BC130285 AAI30286 BQ021667 M92439 AAA67549 XM_006711915 XP_006711978 XM_006711916 XP_006711979 XM_011532473 XP_011530775 XM_011532474 XP_011530776 NM_133259 NP_573566
Function May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane. Note=Seems to be predominantly mitochondrial.
Tissue Specificity Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11827465, ECO:0000269|PubMed:15139850}.

Gp130/IL6ST BioAssay™ ELISA K, Human - 143856 from USBiological Life Science

Sensitivity < 10 pg/ml
Range 125pg/ml-8000pg/ml

Gp130/IL6ST BioAssay™ ELISA Kit, Mouse - 143857 from USBiological Life Science

Category ELISA Kit
Sensitivity < 10 pg/ml
Range 125pg/ml-8000pg/ml

gp130 (Glucoprotein 130), Human, ELISA Kit - E-EL-H1988 from ARP American Research Products

Category ELISA Kit
Prices $617.40
Sizes 96 t

Gp130/IL6ST ELISA K, Human, ELISA Kit - PB-0367 from ARP American Research Products

Category ELISA Kit
Prices $418.00
Sizes 96 t
Sensitivity < 10 pg/ml
Range 125pg/ml-8000pg/ml

Glucoprotein 130, gp130, Mouse, ELISA Kit - E-EL-M0560 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 75
Range 125-8000pg/mL

Glucoprotein 130, gp130, Rat, ELISA Kit - E-EL-R0427 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

gp130 (Glucoprotein 130), Rabbit, ELISA Kit - E-EL-RB1340 from ARP American Research Products

Category ELISA Kit
Prices $773.00
Sizes 96 t

gp130 (Glucoprotein 130), Chicken, ELISA Kit - E-EL-Ch1073 from ARP American Research Products

Category ELISA Kit
Prices $773.00
Sizes 96 t

gp130 (Glucoprotein 130), Pig, ELISA Kit - E-EL-P0944 from ARP American Research Products

Category ELISA Kit
Prices $773.00
Sizes 96 t

Glucoprotein 130, gp130, Sheep, ELISA Kit - E-EL-S0559 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

gp130 (Glucoprotein 130), Monkey, ELISA Kit - E-EL-MK0800 from ARP American Research Products

Category ELISA Kit
Prices $773.00
Sizes 96 t

Human gp130 ELISA Kit - HG0223 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine gp130 ELISA Kit - AG0223 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Leucine Rich PPR Motif Containing Protein (LRPPRC), ELISA Kit - MBS2025016 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.122ng/mL.
Range 0.313-20ng/mL

leucine-rich PPR-motif containing, ELISA Kit - MBS9335598 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Leucine Rich PPR Motif Containing Protein (LRPPRC) - SEJ931Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.122ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Glucoprotein 130 ELISA - E01G0216 from BlueGene Biotech

Category ELISA Kit
Sensitivity 1.0 ng/mL

ELISA Kit for Leucine Rich PPR Motif Containing Protein (LRPPRC) - SEJ931Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.122ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

GP130 - ABE-155-01 from Nordic BioSite

Sensitivity 78 pg/ml
Range 156-10000 pg/ml

Human LRPPRC ELISA Kit (Sandwich ELISA) - LS-F25567 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.122 ng/ml
Range 0.313-20 ng/ml

Human Gp130/IL6ST ELISA Kit - EA100242 from Acris Antibodies

Category ELISA Kit
Prices $389.00
Sizes 1 kit
Range 10

Human gp130 ELISA KIT - orb339795 from Biorbyt

Category ELISA Kit
Prices $748.00, $2,992.00, $5,687.00
Sizes 96 test, 480 test, 960 test
Sensitivity 0.516 ng/ml
Range 0.938ng/ml-60ng/ml

Human Gp130 ELISA Kit - orb154573 from Biorbyt

Category ELISA Kit
Prices $612.00
Sizes 96 well
Sensitivity < 10pg/ml
Range 125pg/ml-8000pg/ml

Human gp130 ELISA Kit - abx571975 from Abbexa

Category ELISA Kit
Sensitivity 0.115 ng/ml
Range 0.313 ng/ml - 20 ng/ml

Gp130/IL6ST - EKH0308 from Nordic BioSite

Sensitivity 0.15ng/ml
Range 0.25-16ng/ml
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