ADRA1A

Gene Symbol ADRA1A
Entrez Gene 100009237
Alt Symbol -
Species Rabbit
Gene Type protein-coding
Description adrenoceptor alpha 1A
Other Description adrenergic, alpha-1A-, receptor|alpha 1A-adrenoreceptor|alpha 1a-adrenoceptor|alpha-1A adrenergic receptor|alpha-1A adrenoceptor|alpha-1A adrenoreceptor|alpha-1A-adrenergic receptor|alpha-1C adrenergic receptor
Swissprots O02824
Accessions O02824 AF157505 AAF80168 AF157506 AAF80169 S75999 AAD14204 U81982 AAB61334 NM_001082380 NP_001075849
Function This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity). {ECO:0000250}.
Subcellular Location Nucleus membrane; Multi-pass membrane protein. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes (By similarity). {ECO:0000250}.
Tissue Specificity Abundant in liver, vas deferens, brain, and aorta, but not in heart.
Top Pathways Calcium signaling pathway, Vascular smooth muscle contraction, Salivary secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

Alpha-1A adrenergic receptor, ADRA1A, Rabbit, ELISA Kit - E1298Rb from ARP American Research Products

Category ELISA Kit
Prices $915.00
Sizes 96 t

Rabbit ADRA1A (Adrenergic Receptor alpha-1A ) ELISA Kit - E-EL-RB2249 from Elabscience

Category ELISA Kit
Range ~

ADRA1A, ELISA Kit - MBS2509451 from MyBioSource

Category ELISA Kit
Prices $450.00, $535.00, $2,255.00, $3,975.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 75pg/mL
Range 125-8000pg/mL

adrenergic, alpha-1A-, receptor, ELISA Kit - MBS701733 from MyBioSource

Category ELISA Kit
Prices $250.00, $590.00, $855.00, $3,110.00, $5,890.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of rat ADRA1A is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 15.6 pg/ml -1000 pg/ml.

Rabbit ADRA1A (Adrenergic Receptor alpha-1A ) ELISA Kit - E-EL-RB2249 from Iwai North America Inc.

Category ELISA Kit
Prices $722.50
Sizes 1 kit
Sensitivity N/A

Rabbit ADRA1A ELISA Kit - E074625 from Biobool

Category ELISA Kit

ADRA1A ELISA Kit (Rat) (OKCA01834) - OKCA01834 from Aviva Systems Biology

Category ELISA Kit
Prices $705.00
Sizes 96 wells
Sensitivity 3.9 pg/mL
Range 15.6 - 1,000 pg/mL
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