SEPT7

Gene Symbol SEPT7
Entrez Gene 989
Alt Symbol CDC10, CDC3, NBLA02942, SEPT7A
Species Human
Gene Type protein-coding
Description septin 7
Other Description CDC10 (cell division cycle 10, S. cerevisiae, homolog)|CDC10 protein homolog|septin 7 variant 4|septin-7
Swissprots Q6NX50 Q52M76 Q16181
Accessions EAW94059 EAW94060 EAW94061 EAW94062 Q16181 AA853468 AB073389 BAE45719 AB209677 BAD92914 AI651908 AK223225 AK223241 AK290545 BAF83234 AK297883 BAG60206 AK298453 BAG60668 AK300601 BAG62298 AL050392 CAI46224 BC022442 BC025987 AAH25987 BC067264 AAH67264 BC093640 AAH93640 BC093642 AAH93642 BC107718 AAI07719 BI669760 BP280069 BQ229116 BQ232357 BX435313 BX571755 CAE11880 BX648365 DA352853 DC414394 DQ232879 ABB17294 HQ258243 ADR82997 KF305319 AHX84171 S72008 AAB31337 XM_006715806 XP_006715869 XM_011515656 XP_011513958 XM_011515657 XP_011513959 XM_011515658 XP_011513960 XM_011515659 XP_011513961 XM_011515660 XP_011513962 XM_011515661 XP_011513963 XM_011515662 XP_011513964 XM_011515663 XP_011513965 NM_001011553 NP_001011553 NM_001242956 NP_001229885 NM_001788 NP_001779
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. {ECO:0000269|PubMed:17803907, ECO:0000269|PubMed:18460473}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18460473}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:18460473}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18460473}. Cleavage furrow {ECO:0000269|PubMed:18460473}. Midbody {ECO:0000269|PubMed:18460473}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Note=Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers (By similarity). {ECO:0000250}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:15915442}.

Septin 7 (H-120) - sc-20620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Septin 7 (H-120): sc-20620. Double immunofluorescent staining of methanol fixed human retinal pigment epithelial (RPE) cells using acetylated α Tubulin (6-11B-1): sc-23950 and donkey anti-mouse IgG-CFL 555: sc-362268 showing cilia staining (red immunofluorescence), Septin 7 (H-120): sc-20620 and donkey anti-rabbit IgG-FITC: sc-2090 showing base of cilia staining (green immunofluorescence) and Hoechst 33342: sc-391054 nuclear counterstain (blue immunofluorescence). Image kindly provided by Moshe Kim, Department of Cell Biology, Hospital for Sick Children (Toronto, Canada)

Septin 7 (N-12) - sc-20419 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Septin 7 (D-12) - sc-20420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SEPT7 antibody - ab138053 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SEPT7 antibody (ab138053) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-SEPT7 antibody - ab66964 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SEPT7 antibody (ab66964) at 1/500 dilutionLane 1 : Transfected 293T cell lysateLane 2 : non Transfected 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-SEPT7 antibody [EPR12610] - ab175229 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12610
All lanes : Anti-SEPT7 antibody [EPR12610] (ab175229) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : HeLa cell lysateLane 3 : MCF7 cell lysateLane 4 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-SEPT7 / Septin 7 Antibody (aa75-125) IHC-plus™ - LS-B11580 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-SEPT7 / Septin 7 Antibody (N-Terminus) - LS-C144763 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT7 / Septin 7 Antibody (Met368) - LS-C192138 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SEPT7 / Septin 7 Antibody (aa421-436) - LS-C194049 from LifeSpan Bioscience

Prices $905.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SEPT7 / Septin 7 Antibody (aa322-334) - LS-C87364 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.5 ug/ml) staining of nuclear HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

Anti-SEPT7 / Septin 7 Antibody (aa319-368) - LS-C200653 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HUVEC cells using SEPT7 antibody.

Anti-SEPT7 / Septin 7 Antibody (aa387-437) - LS-C290854 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse Septin 7 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-Septin 7 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 1 second.

Anti-SEPT7 / Septin 7 Antibody (aa1-278) - LS-C185414 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: MOLT4 . 7.5% SDS PAGE. Septin 7 / SEPT7 antibody diluted at 1:500

Anti-SEPT7 / Septin 7 Antibody - LS-C346129 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using SEPT7 antibody.

Anti-SEPT7 / Septin 7 Antibody - LS-C335403 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SEPT7 antibody.

Anti-SEPT7 / Septin 7 Antibody (aa192-437) - LS-C185413 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded GASTRIC CA using 39331 antibody at 1:100 dilution.

Anti-SEPT7 / Septin 7 Antibody (aa350-399) IHC-plus™ - LS-B9870 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SEPT7 / Septin 7 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Septin-7 Antibody - NBP1-85730 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Septin-7 Antibody - NBP1-85731 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Septin-7 Antibody [NBP1-85731] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Septin-7 Antibody - NBP1-06077 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Septin-7 Antibody [NBP1-06077] (0.5ug/ml) staining of nuclear HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Septin-7 Antibody - H00000989-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Septin-7 Antibody [H00000989-B01P] - Analysis of SEPT7 expression in transfected 293T cell line by SEPT7 polyclonal antibody. Lane 1: SEPT7 transfected lysate(45.98 KDa). Lane 2: Non-transfected lysate.

CDC10 Polyclonal Antibody - bs-7741R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti CDC10/Septin 7 Polyclonal Antibody, Unconjugated (bs-7741R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Anti-SEPT7 antibody produced in rabbit - HPA029524 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SEPT7: <B>Cat. No. HPA029524</B>: Immunohistochemical staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.

Anti-SEPT7 antibody produced in rabbit - HPA023309 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SEPT7: <B>Cat. No. HPA023309</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.
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