| Gene Symbol |
SEPT7
|
| Entrez Gene |
989
|
| Alt Symbol |
CDC10, CDC3, NBLA02942, SEPT7A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
septin 7
|
| Other Description |
CDC10 (cell division cycle 10, S. cerevisiae, homolog)|CDC10 protein homolog|septin 7 variant 4|septin-7
|
| Swissprots |
Q6NX50 Q52M76 Q16181
|
| Accessions |
EAW94059 EAW94060 EAW94061 EAW94062 Q16181 AA853468 AB073389 BAE45719 AB209677 BAD92914 AI651908 AK223225 AK223241 AK290545 BAF83234 AK297883 BAG60206 AK298453 BAG60668 AK300601 BAG62298 AL050392 CAI46224 BC022442 BC025987 AAH25987 BC067264 AAH67264 BC093640 AAH93640 BC093642 AAH93642 BC107718 AAI07719 BI669760 BP280069 BQ229116 BQ232357 BX435313 BX571755 CAE11880 BX648365 DA352853 DC414394 DQ232879 ABB17294 HQ258243 ADR82997 KF305319 AHX84171 S72008 AAB31337 XM_006715806 XP_006715869 XM_011515656 XP_011513958 XM_011515657 XP_011513959 XM_011515658 XP_011513960 XM_011515659 XP_011513961 XM_011515660 XP_011513962 XM_011515661 XP_011513963 XM_011515662 XP_011513964 XM_011515663 XP_011513965 NM_001011553 NP_001011553 NM_001242956 NP_001229885 NM_001788 NP_001779
|
| Function |
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. {ECO:0000269|PubMed:17803907, ECO:0000269|PubMed:18460473}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18460473}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:18460473}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18460473}. Cleavage furrow {ECO:0000269|PubMed:18460473}. Midbody {ECO:0000269|PubMed:18460473}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Note=Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:15915442}.
|