Gene Symbol |
AARS2
|
Entrez Gene |
57505
|
Alt Symbol |
AARSL, COXPD8, LKENP, MT-ALARS, MTALARS
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
alanyl-tRNA synthetase 2, mitochondrial
|
Other Description |
alanine tRNA ligase 2, mitochondrial (putative)|alanine--tRNA ligase, mitochondrial|alanyl-tRNA synthetase 2, mitochondrial (putative)|alanyl-tRNA synthetase like|probable alanyl-tRNA synthetase, mitochondrial
|
Swissprots |
Q9ULF0 Q8N198 Q96D02 A2RRN5 Q5JTZ9
|
Accessions |
EAX04268 Q5JTZ9 AB033096 BAA86584 AL536467 BC013593 AAH13593 BC021131 BC033169 AAH33169 BC041026 BC128175 AAI28176 BC131728 AAI31729 BF768723 CN343332 XM_005249245 XP_005249302 XM_011514764 XP_011513066 XR_241907 NM_020745 NP_065796
|
Function |
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. {ECO:0000255|HAMAP-Rule:MF_03133}.
|
Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03133, ECO:0000269|PubMed:21549344}.
|
Top Pathways |
Aminoacyl-tRNA biosynthesis
|