Gene Symbol |
HIST1H2AH
|
Entrez Gene |
85235
|
Alt Symbol |
H2A/S, H2AFALii, H2AH, dJ86C11.1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
histone cluster 1, H2ah
|
Other Description |
H2A histone family member|histone H2A type 1-H|histone H2A/s
|
Swissprots |
Q96KK5
|
Accessions |
AAN59969 EAX03087 Q96KK5 AK312232 BAG35165 BC093849 AAH93849 BC093851 AAH93851 BC134366 AAI34367 BC141469 AAI41470 BC148293 AAI48294 NM_080596 NP_542163
|
Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
Subcellular Location |
Nucleus. Chromosome.
|
Top Pathways |
Systemic lupus erythematosus, Alcoholism
|