| Gene Symbol |
HIST1H2AH
|
| Entrez Gene |
85235
|
| Alt Symbol |
H2A/S, H2AFALii, H2AH, dJ86C11.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H2ah
|
| Other Description |
H2A histone family member|histone H2A type 1-H|histone H2A/s
|
| Swissprots |
Q96KK5
|
| Accessions |
AAN59969 EAX03087 Q96KK5 AK312232 BAG35165 BC093849 AAH93849 BC093851 AAH93851 BC134366 AAI34367 BC141469 AAI41470 BC148293 AAI48294 NM_080596 NP_542163
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Alcoholism
|