SDHAF3

Gene Symbol SDHAF3
Entrez Gene 57001
Alt Symbol ACN9, DC11, Sdh7
Species Human
Gene Type protein-coding
Description succinate dehydrogenase complex assembly factor 3
Other Description ACN9 homolog|SDH assembly factor 3|protein ACN9 homolog, mitochondrial|succinate dehydrogenase assembly factor 3, mitochondrial
Swissprots A4D1J3 Q9NRP4 Q75MD6
Accessions AAS07570 EAL24120 EAW76739 EAW76740 Q9NRP4 AF201933 AAF86869 BC020621 AAH20621 BC022858 AAH22858 BC028409 CD557710 XM_011516415 XP_011514717 NM_020186 NP_064571
Function Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. {ECO:0000250|UniProtKB:Q04401, ECO:0000250|UniProtKB:Q8SZ16}.
Subcellular Location Mitochondrion matrix {ECO:0000250|UniProtKB:Q04401}.

ACN9 CRISPR/Cas9 KO Plasmid (h) - sc-412747 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 HDR Plasmid (h) - sc-412747-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 Double Nickase Plasmid (h) - sc-412747-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 Double Nickase Plasmid (h2) - sc-412747-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 CRISPR Activation Plasmid (h) - sc-412747-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 CRISPR Activation Plasmid (h2) - sc-412747-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 Lentiviral Activation Particles (h) - sc-412747-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 Lentiviral Activation Particles (h2) - sc-412747-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ACN9 siRNA (h) - sc-89725 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACN9 shRNA Plasmid (h) - sc-89725-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ACN9 shRNA (h) Lentiviral Particles - sc-89725-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN2721 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2721 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04159 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04159

ACN9 siRNA (Human) - CRJ1283 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACN9 - MBS8206640 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACN9 (NM_020186.2) - SHH230314 from Creative biogene

Category siRNA
Species Reactivities Human

Human ACN9 siRNA - orb271784 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACN9 shRNA Plasmid (Human) - CHJ1283 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACN9 miRNA 3'UTR clone - MiUTR3H-13502 from Creative biogene

Species Reactivities Human
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