ARHGAP10

Gene Symbol ARHGAP10
Entrez Gene 79658
Alt Symbol GRAF2, PS-GAP, PSGAP
Species Human
Gene Type protein-coding
Description Rho GTPase activating protein 10
Other Description GTPase regulator associated with focal adhesion kinase 2|graf-related protein 2|rho GTPase-activating protein 10|rho-type GTPase-activating protein 10
Swissprots Q96S75 Q96EV3 Q2VPC4 A1A4S6 A1L0S5 Q2VPC5
Accessions A1A4S6 EAX05009 EAX05010 AB050785 BAB61771 AK024549 BAB14924 AK123034 BAG53857 AK123785 AK130998 AK304458 BAG65274 AL834360 CAD39024 BC011920 AAH11920 BC047914 AAH47914 BC106018 AAI06019 BC109029 AAI09030 BC109030 AAI09031 BC126899 AAI26900 BC128055 AAI28056 BX647727 CR457328 CAG33609 XM_005263215 XP_005263272 XM_005263217 XP_005263274 XM_011532243 XP_011530545 XM_011532244 XP_011530546 NM_024605 NP_078881
Function GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Association to cell membrane is dependent on PH domain. {ECO:0000250}.
Tissue Specificity High levels of expression in heart and skeletal muscle. {ECO:0000269|PubMed:11432776}.
Top Pathways Bacterial invasion of epithelial cells

ARHGAP10 (D-16) - sc-160139 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARHGAP10 (N-13) - sc-160141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ARHGAP10 (N-13): sc-160141. Western blot analysis of ARHGAP10 expression in HISM whole cell lysate.

Anti-ARHGAP10 antibody - ab150856 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli and cytoplasm. Recommended concentration of ab150856 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-ARHGAP10 Antibody (aa237-263, FITC) - LS-C251632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa237-263, AP) - LS-C251626 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa237-263, Biotin) - LS-C251631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa237-263, APC) - LS-C251630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa237-263, Azide-free, HRP) - LS-C251633 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa237-263, PE) - LS-C251634 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa240-267) - LS-C319570 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 Antibody (aa237-263) - LS-C156465 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ARHGAP10 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

ARHGAP10 Antibody - NBP2-14503 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ARHGAP10 Antibody [NBP2-14503] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm.

ANTI-ARHGAP10 (CENTER) antibody produced in rabbit - SAB1301150 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARHGAP10 antibody produced in rabbit - HPA039589 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ARHGAP10:<B>Cat. No. HPA039589</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells.

ARHGAP10 Antibody - middle region (OAAB00712) - OAAB00712 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ARHGAP10-Antibody-Center - AP10695b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ARHGAP10 Antibody (Center) (Cat. #AP10695b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ARHGAP10 antibody detected the ARHGAP10 protein (arrow).

ARHGAP10 antibody - 70R-15801 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

ARHGAP10 Polyclonal Antibody - A3689 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

ARHGAP10 / GRAF2 (Center) antibody - AP50232PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ARHGAP10 antibody (Center) (Cat. #AP50232PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ARHGAP10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Anti-ARHGAP10, Polyclonal Antibody - 25-A3689 from ARP American Research Products

Prices $299.00, $449.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

ARHGAP10 antibody - 55139-1-AP from Proteintech Group

Prices $279.00
Sizes con: 60 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP( ARHGAP10 Antibody) at dilution of 1:1000

ARHGAP10 antibody - STJ26449 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

ARHGAP10 - A3689 from NeoScientific

Prices $480.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

ARHGAP10 - MBS9127466 from MyBioSource

Prices $285.00, $555.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

ARHGAP10, Polyclonal Antibody - MBS6012020 from MyBioSource

Prices $550.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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