| Gene Symbol |
TOR1AIP1
|
| Entrez Gene |
26092
|
| Alt Symbol |
LAP1, LAP1B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
torsin A interacting protein 1
|
| Other Description |
lamin-associated protein 1B|lamina associated polypeptide 1B|lamina-associated polypeptide 1B|torsin-1A-interacting protein 1
|
| Swissprots |
Q5JTV6 Q9NV52 Q9HAJ1 B0QZ57 Q9Y3X5 Q8IZ65 Q9H8Y6 A8K630 Q5JTV8
|
| Accessions |
EAW91067 EAW91068 Q5JTV8 AK001780 BAA91906 AK021613 BAB13855 AK023204 BAB14461 AK291495 BAF84184 AK310012 AL050126 CAB43282 AL598529 AW298193 BC023247 AAH23247 BQ435161 BX369105 CN360425 JF432539 ADZ15756 XM_011509403 XP_011507705 XM_011509404 XP_011507706 NM_001267578 NP_001254507 NM_015602 NP_056417 NM_032678
|
| Function |
Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina. {ECO:0000269|PubMed:23569223}.
|
| Subcellular Location |
Nucleus inner membrane {ECO:0000269|PubMed:12061773, ECO:0000269|PubMed:24275647}; Single-pass membrane protein {ECO:0000269|PubMed:12061773, ECO:0000269|PubMed:24275647}.
|
![Western Blot: LAP1B Overexpression Lysate (Adult Normal) [NBP2-07143] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LAP1B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9843_LAP1B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07143-img0001.jpg)