Gene Symbol | TOR1AIP1 |
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Entrez Gene | 26092 |
Alt Symbol | LAP1, LAP1B |
Species | Human |
Gene Type | protein-coding |
Description | torsin A interacting protein 1 |
Other Description | lamin-associated protein 1B|lamina associated polypeptide 1B|lamina-associated polypeptide 1B|torsin-1A-interacting protein 1 |
Swissprots | Q5JTV6 Q9NV52 Q9HAJ1 B0QZ57 Q9Y3X5 Q8IZ65 Q9H8Y6 A8K630 Q5JTV8 |
Accessions | EAW91067 EAW91068 Q5JTV8 AK001780 BAA91906 AK021613 BAB13855 AK023204 BAB14461 AK291495 BAF84184 AK310012 AL050126 CAB43282 AL598529 AW298193 BC023247 AAH23247 BQ435161 BX369105 CN360425 JF432539 ADZ15756 XM_011509403 XP_011507705 XM_011509404 XP_011507706 NM_001267578 NP_001254507 NM_015602 NP_056417 NM_032678 |
Function | Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina. {ECO:0000269|PubMed:23569223}. |
Subcellular Location | Nucleus inner membrane {ECO:0000269|PubMed:12061773, ECO:0000269|PubMed:24275647}; Single-pass membrane protein {ECO:0000269|PubMed:12061773, ECO:0000269|PubMed:24275647}. |
LAP1B CRISPR/Cas9 KO Plasmid (h) - sc-408613 from Santa Cruz Biotechnology
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LAP1B HDR Plasmid (h) - sc-408613-HDR from Santa Cruz Biotechnology
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LAP1B Double Nickase Plasmid (h) - sc-408613-NIC from Santa Cruz Biotechnology
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LAP1B Double Nickase Plasmid (h2) - sc-408613-NIC-2 from Santa Cruz Biotechnology
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LAP1B CRISPR Activation Plasmid (h) - sc-408613-ACT from Santa Cruz Biotechnology
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LAP1B CRISPR Activation Plasmid (h2) - sc-408613-ACT-2 from Santa Cruz Biotechnology
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LAP1B Lentiviral Activation Particles (h) - sc-408613-LAC from Santa Cruz Biotechnology
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LAP1B Lentiviral Activation Particles (h2) - sc-408613-LAC-2 from Santa Cruz Biotechnology
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LAP1B siRNA (h) - sc-88465 from Santa Cruz Biotechnology
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LAP1B shRNA Plasmid (h) - sc-88465-SH from Santa Cruz Biotechnology
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LAP1B shRNA (h) Lentiviral Particles - sc-88465-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU066211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21833 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21833 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10580 from Sigma-Aldrich
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TOR1AIP1 siRNA (Human) - CRH8704 from Cohesion Biosciences
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TOR1AIP1 - MBS8214554 from MyBioSource
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shRNA set against Human TOR1AIP1 (NM_015602.3) - SHH432944 from Creative biogene
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Human TOR1AIP1 siRNA - orb269206 from Biorbyt
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TOR1AIP1 shRNA Plasmid (Human) - CHH8704 from Cohesion Biosciences
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TOR1AIP1 miRNA 3'UTR clone - MiUTR3H-13276 from Creative biogene
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