Gene Symbol |
PTGIR
|
Entrez Gene |
5739
|
Alt Symbol |
IP, PRIPR
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
prostaglandin I2 (prostacyclin) receptor (IP)
|
Other Description |
PGI receptor|PGI2 receptor|prostacyclin receptor|prostaglandin I2 receptor|prostanoid IP receptor
|
Swissprots |
P43119
|
Accessions |
BAA07325 CAH05338 EAW57432 EAW57433 P43119 AK315278 BAG37688 AY242134 AAO92301 BC075814 AAH75814 BC110342 AAI10343 BQ185457 D25418 BAA05008 D29634 BAA06110 DA652875 L29016 AAA36448 XM_005259093 XP_005259150 XM_005259095 XP_005259152 XR_243945 XR_430206 XR_935844 NM_000960 NP_000951
|
Function |
Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Vascular smooth muscle contraction, Neuroactive ligand-receptor interaction
|