Gene Symbol | PTGIR |
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Entrez Gene | 5739 |
Alt Symbol | IP, PRIPR |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin I2 (prostacyclin) receptor (IP) |
Other Description | PGI receptor|PGI2 receptor|prostacyclin receptor|prostaglandin I2 receptor|prostanoid IP receptor |
Swissprots | P43119 |
Accessions | BAA07325 CAH05338 EAW57432 EAW57433 P43119 AK315278 BAG37688 AY242134 AAO92301 BC075814 AAH75814 BC110342 AAI10343 BQ185457 D25418 BAA05008 D29634 BAA06110 DA652875 L29016 AAA36448 XM_005259093 XP_005259150 XM_005259095 XP_005259152 XR_243945 XR_430206 XR_935844 NM_000960 NP_000951 |
Function | Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Vascular smooth muscle contraction, Neuroactive ligand-receptor interaction |
IP Receptor CRISPR/Cas9 KO Plasmid (h) - sc-404135 from Santa Cruz Biotechnology
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IP Receptor HDR Plasmid (h) - sc-404135-HDR from Santa Cruz Biotechnology
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IP Receptor Double Nickase Plasmid (h) - sc-404135-NIC from Santa Cruz Biotechnology
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IP Receptor Double Nickase Plasmid (h2) - sc-404135-NIC-2 from Santa Cruz Biotechnology
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IP Receptor CRISPR Activation Plasmid (h) - sc-404135-ACT from Santa Cruz Biotechnology
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IP Receptor CRISPR Activation Plasmid (h2) - sc-404135-ACT-2 from Santa Cruz Biotechnology
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IP Receptor Lentiviral Activation Particles (h) - sc-404135-LAC from Santa Cruz Biotechnology
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IP Receptor Lentiviral Activation Particles (h2) - sc-404135-LAC-2 from Santa Cruz Biotechnology
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IP Receptor siRNA (h) - sc-40175 from Santa Cruz Biotechnology
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IP Receptor shRNA Plasmid (h) - sc-40175-SH from Santa Cruz Biotechnology
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IP Receptor shRNA (h) Lentiviral Particles - sc-40175-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN17673 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17673 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06350 from Sigma-Aldrich
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PTGIR siRNA (Human) - CRH3881 from Cohesion Biosciences
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PTGIR RNAi - H00005739-R02 from Novus Biologicals
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IP Receptor CRISPR/Cas9 KO Plasmid (h2) - sc-404135-KO-2 from Santa Cruz Biotechnology
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IP Receptor HDR Plasmid (h2) - sc-404135-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human PTGIR (NM_000960.3) - SHH386088 from Creative biogene
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shRNA set against Human PTGIR(NM_000960.3) - SHR106852 from Creative biogene
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PTGIR shRNA Plasmid (Human) - CHH3881 from Cohesion Biosciences
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PTGIR miRNA 3'UTR clone - MiUTR1H-08426 from Creative biogene
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