Gene Symbol | PRDM1 |
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Entrez Gene | 639 |
Alt Symbol | BLIMP1, PRDI-BF1 |
Species | Human |
Gene Type | protein-coding |
Description | PR domain containing 1, with ZNF domain |
Other Description | B-lymphocyte-induced maturation protein 1|BLIMP-1|PR domain zinc finger protein 1|PRDI-binding factor-1|beta-interferon gene positive-regulatory domain I binding factor |
Swissprots | Q86WM7 E1P5E0 B2REA6 O75626 |
Accessions | ABK41898 EAW48419 EAW48420 EAW48421 EAW48422 O75626 AF084199 AAC33300 AK129768 AK289556 BAF82245 AK301341 BAG62889 AL832963 CAH56276 AY198414 AAO45623 AY198415 AAO45624 BC103832 AAI03833 BC103833 AAI03834 BC103834 AAI03835 BC103835 AAI03836 EF151143 ABL96617 EU831954 ACE87395 EU832048 ACE86710 XM_005267094 XP_005267151 XM_006715550 XP_006715613 XM_011536062 XP_011534364 XM_011536063 XP_011534365 XM_011536064 XP_011534366 NM_001198 NP_001189 NM_182907 NP_878911 |
Function | Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569). {ECO:0000269|PubMed:12626569, ECO:0000269|PubMed:1851123}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm {ECO:0000269|PubMed:21421998}. |
Blimp-1 CRISPR/Cas9 KO Plasmid (h) - sc-400585 from Santa Cruz Biotechnology
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Blimp-1 HDR Plasmid (h) - sc-400585-HDR from Santa Cruz Biotechnology
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Blimp-1 Double Nickase Plasmid (h) - sc-400585-NIC from Santa Cruz Biotechnology
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Blimp-1 Double Nickase Plasmid (h2) - sc-400585-NIC-2 from Santa Cruz Biotechnology
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Blimp-1 CRISPR Activation Plasmid (h) - sc-400585-ACT from Santa Cruz Biotechnology
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Blimp-1 CRISPR Activation Plasmid (h2) - sc-400585-ACT-2 from Santa Cruz Biotechnology
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Blimp-1 Lentiviral Activation Particles (h) - sc-400585-LAC from Santa Cruz Biotechnology
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Blimp-1 Lentiviral Activation Particles (h2) - sc-400585-LAC-2 from Santa Cruz Biotechnology
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Blimp-1 siRNA (h) - sc-37714 from Santa Cruz Biotechnology
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Blimp-1 shRNA Plasmid (h) - sc-37714-SH from Santa Cruz Biotechnology
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Blimp-1 shRNA (h) Lentiviral Particles - sc-37714-V from Santa Cruz Biotechnology
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BLIMP1/PRDM1 RNAi - H00000639-R01V from Novus Biologicals
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BLIMP1/PRDM1 RNAi - H00000639-R01 from Novus Biologicals
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BLIMP1/PRDM1 RNAi - H00000639-R02 from Novus Biologicals
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MISSION® esiRNA - EHU130211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1961 from Sigma-Aldrich
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PRDM1 siRNA (Human) - CRH0435 from Cohesion Biosciences
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shRNA set against Human PRDM1 (NM_182907.2) - SHH382136 from Creative biogene
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Human PRDM1 siRNA - orb260937 from Biorbyt
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PRDM1 shRNA Plasmid (Human) - CHH0435 from Cohesion Biosciences
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PRDM1 miRNA 3'UTR clone - MiUTR3H-05955 from Creative biogene
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