PRDM1

Gene Symbol PRDM1
Entrez Gene 639
Alt Symbol BLIMP1, PRDI-BF1
Species Human
Gene Type protein-coding
Description PR domain containing 1, with ZNF domain
Other Description B-lymphocyte-induced maturation protein 1|BLIMP-1|PR domain zinc finger protein 1|PRDI-binding factor-1|beta-interferon gene positive-regulatory domain I binding factor
Swissprots Q86WM7 E1P5E0 B2REA6 O75626
Accessions ABK41898 EAW48419 EAW48420 EAW48421 EAW48422 O75626 AF084199 AAC33300 AK129768 AK289556 BAF82245 AK301341 BAG62889 AL832963 CAH56276 AY198414 AAO45623 AY198415 AAO45624 BC103832 AAI03833 BC103833 AAI03834 BC103834 AAI03835 BC103835 AAI03836 EF151143 ABL96617 EU831954 ACE87395 EU832048 ACE86710 XM_005267094 XP_005267151 XM_006715550 XP_006715613 XM_011536062 XP_011534364 XM_011536063 XP_011534365 XM_011536064 XP_011534366 NM_001198 NP_001189 NM_182907 NP_878911
Function Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569). {ECO:0000269|PubMed:12626569, ECO:0000269|PubMed:1851123}.
Subcellular Location Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm {ECO:0000269|PubMed:21421998}.

Blimp-1/PRDI-BF1 (C14A4) Rabbit mAb - 9115 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C14A4
Western blot analysis of extracts from Karpas 620, SR and H929 cell lines using Blimp-1/PRDI-BF1 (C14A4) Rabbit mAb.

Blimp-1 (C-7) - sc-398699 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Blimp-1 (C-7): sc-398699. Western blot analysis of Blimp-1 expression in BJAB (A), HeLa (B) and Ramos (C) whole cell lysates and HL-60 nuclear extract (D).

Blimp-1 (6D3) - sc-47732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Blimp-1 (6D3): sc-47732. Western blot analysis of Blimp-1 expression in BJAB (A), HeLa (B), Ramos (C), U-937 (D) and HL-60 (E) nuclear extracts.

Blimp-1 (3H2E8) - sc-66015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Blimp-1 (3H2E8): sc-66015. Western blot analysis of Blimp-1 expression in non-transfected: sc-110760 (A) and human Blimp-1 transfected: sc-176917 (B) 293 whole cell lysates.

Blimp-1 (C-21) - sc-13206 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Blimp-1 (C-21): sc-13206. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Blimp-1 (H-150) - sc-25380 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Blimp-1 (N-20) - sc-13203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Blimp-1 (N-20) PE: sc-13203 PE. Intracellular FCM analysis of fixed and permeabilized BJAB cells. Black line histogram represents the isotype control, normal goat IgG: sc-3992.

Anti-PRDM1/Blimp1 antibody - ab119401 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRDM1/Blimp1 antibody (ab119401) at 1/500 dilutionLane 1 : Jurkat cell extractLane 2 : Raji cell extract

Anti-PRDM1/Blimp1 antibody [3H2-E8] (Biotin) - ab81961 from Abcam

Prices $372.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H2-E8

Anti-PRDM1/Blimp1 antibody [5E7] - ab96479 from Abcam

Host Mouse
Clonality Monoclonal
Clone 5E7
All lanes : Anti-PRDM1/Blimp1 antibody [5E7] (ab96479) at 1/500 dilutionLane 1 : Raji cell lysateLane 2 : Raji cell lysateLane 3 : L1210 cell lysateLane 4 : TPH1 cell lysate

Anti-PRDM1/Blimp1 antibody [EPR16655] - ab198287 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16655
Immunohistochemical analysis of paraffin-embedded Human diffuse large B cell lymphoma tissue labeling PRDM1/Blimp1 using ab198287 at 1/500 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution. Nuclear staining on Human diffuse large B cell lymphoma tissue is observed. Counter stained with Hematoxylin.Negative control: Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/500 dilution.

Anti-BLIMP1 / PRDM1 Antibody (clone 2B10) - LS-C196751 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B10
Western Blot analysis of PRDM1 expression in transfected 293T cell line by PRDM1 monoclonal antibody (M01), clone 2B10.Lane 1: PRDM1 transfected lysate(88 KDa).Lane 2: Non-transfected lysate.

Anti-BLIMP1 / PRDM1 Antibody (aa611-660) IHC-plus™ - LS-B4694 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BLIMP-1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4694 concentration 5 ug/ml.

Anti-BLIMP1 / PRDM1 Antibody (C-Terminus) IHC-plus™ - LS-B10615 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BLIMP1 / PRDM1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-BLIMP1 / PRDM1 Antibody (aa199-409) - LS-C77064 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-BLIMP1 / PRDM1 Antibody (aa199-409, clone 3H2-E8, HRP) - LS-C83858 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H2-E8

Anti-BLIMP1 / PRDM1 Antibody (aa687-789) - LS-C127045 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BLIMP1 / PRDM1 Antibody (aa199-409, clone 3H2-E8, DY650) - LS-C142328 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H2-E8

Anti-BLIMP1 / PRDM1 Antibody (aa37-86) - LS-C31422 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-BLIMP1 / PRDM1 Antibody (aa199-409, clone 3H2-E8, DY488) - LS-C142329 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H2-E8

Anti-BLIMP1 / PRDM1 Antibody (aa199-409, clone 3H2-E8, DY550) - LS-C142330 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H2-E8

Anti-BLIMP1 / PRDM1 Antibody - LS-C143656 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BLIMP1 / PRDM1 Antibody (aa185-199) - LS-C148874 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-BLIMP1 / PRDM1 Antibody (aa778-789) - LS-C112748 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
PRDM1 antibody (1 ug/ml) staining of Human Brain (cerebellum) lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-BLIMP1 / PRDM1 Antibody (aa199-409, clone 3H2-E8) - LS-C2538 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H2-E8
Double IF for Blimp-1 (green) and Ki-67 (proliferation, red) with DAPI counterstain, at 10x magnification (scale bar is 10mum). Positive surface epithelium and centrocytes are labeled.
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