HMGCR

Gene Symbol	HMGCR
Entrez Gene	3156
Alt Symbol	LDLCQ3
Species	Human
Gene Type	protein-coding
Description	3-hydroxy-3-methylglutaryl-CoA reductase
Other Description	3-hydroxy-3-methylglutaryl CoA reductase (NADPH)|3-hydroxy-3-methylglutaryl-Coenzyme A reductase|HMG-CoA reductase|hydroxymethylglutaryl-CoA reductase
Swissprots	B7Z3Y9 Q8N190 P04035
Accessions	AAG21343 AAP72015 CAZ64465 EAW95754 EAW95755 EAW95756 P04035 AA648735 AK292892 BAF85581 AK296499 BAH12375 AK299655 BAG61573 AK312437 BAG35346 AY429541 AY429542 AY429543 BC024180 BC033692 AAH33692 CN278665 DQ890855 ABM81781 DQ894009 ABM84935 M11058 AAA52679 M62627 M62633 XM_011543357 XP_011541659 XM_011543358 XP_011541660 XM_011543359 XP_011541661 NM_000859 NP_000850 NM_001130996 NP_001124468
Function	Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways	Terpenoid backbone biosynthesis, Bile secretion, AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F7315 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Human HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F11637 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 0.313-20 ng/ml

3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMGCR, Human, ELISA Kit - E10451h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Hydroxymethylglutaryl CoA Reductase (HMG-CoAR), Human, ELISA Kit - CSB-E15964h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.195 ng/ml Range 0.78 ng/ml- 50 ng/ml

Human HMGCR ELISA Kit - HH1257 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

3-hydroxy-3-methylglutaryl-Coenzyme A reductase, ELISA Kit - MBS705606 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.195 ng/ml Range 0.78 ng/ml- 50 ng/ml

ELISA Kit for 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) - SED686Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.58ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

ELISA Kit for 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) - SED686Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.132ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Hydroxymethylglutaryl CoA Reductase (HMG-CoAR) ELISA kit - CSB-E15964h from Cusabio Category ELISA Kit Sensitivity 0.195 ng/ml Range 0.78 ng/ml- 50 ng/ml

Human 3-Hydroxy-3-methylglutaryl CoA reductase ELISA - E01H1250 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1ng/mL

ELISA Kit for 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) - SED686Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.58ng/mL. Range 1.563-100ng/mL The standard curve concentrations used for the ELISA's were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL

Rabbit HMG-CoA Reductase / HMGCR ELISA Kit - LS-F15756 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range To be determined

Rat HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F15758 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.625 Range 0.313-20 ng/ml

Mouse HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F15757 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 ng/ml Range 0.313-20 ng/ml

Pig HMG-CoA Reductase / HMGCR ELISA Kit (Custom ELISA) - LS-F15755 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Bovine HMG-CoA Reductase / HMGCR ELISA Kit (Custom ELISA) - LS-F15759 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase ELISA Kit - abx250429 from Abbexa Category ELISA Kit Range 0.78 ng/ml - 50 ng/ml

Rat HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F22322 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.188 ng/ml Range 0.313-20 ng/ml

HMG-CoA (3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase), CLIA Kit - MBS2531483 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313~20ng/mL

Human HMGCR(3-Hydroxy-3-methylglutaryl CoA Reductase) ELISA Kit - E-EL-H2472 from Elabscience Category ELISA Kit Sensitivity 0.38 ng/mL Range 0.63—40 ng/mL

Human HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F25429 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.58 ng/ml Range 0.313-20 ng/ml

Human HMG-CoA Reductase / HMGCR ELISA Kit (Sandwich ELISA) - LS-F26999 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 ng/ml Range 0.313-20 ng/ml

Mouse HMG-CoA Reductase / HMGCR ELISA Kit (Competitive EIA) - LS-F28419 from LifeSpan Bioscience Category ELISA Kit Prices $870.00 Sizes 1 plate Sensitivity 0.1 µg/ml Range 0.313-20 ng/ml

Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase ELISA Kit - EKE52704 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.23 ng/mL Range 0.78-50 ng/mL

HMGCR - EKH2352 from Nordic BioSite Sensitivity 0.469ng/ml Range 0.78-50ng/ml

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