Gene Symbol | PLEKHA1 |
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Entrez Gene | 59338 |
Alt Symbol | TAPP1 |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
Other Description | pleckstrin homology domain-containing family A member 1|tandem PH domain-containing protein 1 |
Swissprots | Q9BVK0 Q9HB21 D3DRE2 B3KQ55 |
Accessions | EAW49315 EAW49316 EAW49317 EAW49318 EAW49319 Q9HB21 AB209407 BAD92644 AF286160 AAG15197 AK057463 BAG51917 AK075159 BAG52077 AK095775 AK314660 BAG37218 AL133603 BC001136 AAH01136 BC041654 BC042458 AAH42458 BE785067 BX647627 CN310748 DA923219 DQ892266 ABM83192 DQ895467 ABM86393 R26739 XM_005270016 XP_005270073 XM_005270019 XP_005270076 XM_005270020 XP_005270077 XM_005270021 XP_005270078 XM_011540017 XP_011538319 XM_011540018 XP_011538320 XM_011540019 XP_011538321 XM_011540020 XP_011538322 XM_011540021 XP_011538323 XM_011540022 XP_011538324 XM_011540023 XP_011538325 XM_011540024 XP_011538326 XM_011540025 XP_011538327 XM_011540026 XP_011538328 NM_001001974 NP_001001974 NM_001195608 NP_001182537 NM_021622 NP_067635 |
Function | Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. {ECO:0000269|PubMed:11001876, ECO:0000269|PubMed:11513726, ECO:0000269|PubMed:14516276}. |
Subcellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. |
Tissue Specificity | Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon. {ECO:0000269|PubMed:11001876, ECO:0000269|PubMed:12101241}. |
Human PLEKHA1 full length protein - ab163705 from Abcam
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Human PLEKHA1 protein fragment - ab163706 from Abcam
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PLEKHA1 Antibody Blocking Peptide - LS-E5694 from LifeSpan Bioscience
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PLEKHA1 Antibody Blocking Peptide - LS-E21008 from LifeSpan Bioscience
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Recombinant Human TAPP1/PLEKHA1 Protein - H00059338-Q01 from Novus Biologicals
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Recombinant Human TAPP1/PLEKHA1 Protein - H00059338-P01 from Novus Biologicals
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PLEKHA1-Antibody-Center-Blocking-Peptide - BP18230c from Abgent, a WuXi AppTec company
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PLEKHA1 Blocking Peptide - 33R-5226 from Fitzgerald
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Human PLEKHA1 Protein - abx068604 from Abbexa
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PLEKHA1 - H00059338-P01-10 from Acris Antibodies
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PLEKHA1 - H00059338-P01-25 from Acris Antibodies
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PLEKHA1 - H00059338-Q01-10 from Acris Antibodies
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PLEKHA1 - H00059338-Q01-25 from Acris Antibodies
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PLEKHA1 fusion protein - Ag0318 from Proteintech Group
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Recombinant Human PLEKHA1, GST-tagged - PLEKHA1-1775H from Creative Biomart
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Recombinant Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) - RPH871Hu01 from Uscn Life Science Inc.
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Recombinant Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) - RPH871Mu01 from Uscn Life Science Inc.
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Recombinant Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1) - RPH871Hu01 from Cloud-clone
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Recombinant Human Pleckstrin homology domain-containing family A member 1(PLEKHA1) - CSB-YP864016HU CSB-EP864016HU CSB-BP864016HU CSB-MP864016HU from Cusabio
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PLEKHA1 Protein - abx163159 from Abbexa
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PLEKHA1 (transcript variant 1) - TP307285 from Acris Antibodies
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Pleckstrin Homology Domain Containing Family A, Member 1 (PLEKHA1), Recombinant Protein - MBS2018406 from MyBioSource
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Pleckstrin homology domain-containing family A member 1 (PLEKHA1), Recombinant Protein - MBS1361998 from MyBioSource
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TAPP1/PLEKHA1 Recombinant Protein Antigen - NBP1-86967PEP from Novus Biologicals
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PLEKHA1 Peptide, Human - M34GP11921H from Creative Peptides
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