PLEKHA1

Gene Symbol PLEKHA1
Entrez Gene 59338
Alt Symbol TAPP1
Species Human
Gene Type protein-coding
Description pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Other Description pleckstrin homology domain-containing family A member 1|tandem PH domain-containing protein 1
Swissprots Q9BVK0 Q9HB21 D3DRE2 B3KQ55
Accessions EAW49315 EAW49316 EAW49317 EAW49318 EAW49319 Q9HB21 AB209407 BAD92644 AF286160 AAG15197 AK057463 BAG51917 AK075159 BAG52077 AK095775 AK314660 BAG37218 AL133603 BC001136 AAH01136 BC041654 BC042458 AAH42458 BE785067 BX647627 CN310748 DA923219 DQ892266 ABM83192 DQ895467 ABM86393 R26739 XM_005270016 XP_005270073 XM_005270019 XP_005270076 XM_005270020 XP_005270077 XM_005270021 XP_005270078 XM_011540017 XP_011538319 XM_011540018 XP_011538320 XM_011540019 XP_011538321 XM_011540020 XP_011538322 XM_011540021 XP_011538323 XM_011540022 XP_011538324 XM_011540023 XP_011538325 XM_011540024 XP_011538326 XM_011540025 XP_011538327 XM_011540026 XP_011538328 NM_001001974 NP_001001974 NM_001195608 NP_001182537 NM_021622 NP_067635
Function Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. {ECO:0000269|PubMed:11001876, ECO:0000269|PubMed:11513726, ECO:0000269|PubMed:14516276}.
Subcellular Location Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.
Tissue Specificity Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon. {ECO:0000269|PubMed:11001876, ECO:0000269|PubMed:12101241}.

TAPP1 CRISPR/Cas9 KO Plasmid (h) - sc-406700 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 HDR Plasmid (h) - sc-406700-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 Double Nickase Plasmid (h) - sc-406700-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 Double Nickase Plasmid (h2) - sc-406700-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 CRISPR Activation Plasmid (h) - sc-406700-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 CRISPR Activation Plasmid (h2) - sc-406700-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 Lentiviral Activation Particles (h) - sc-406700-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 Lentiviral Activation Particles (h2) - sc-406700-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TAPP1 siRNA (h) - sc-63100 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TAPP1 shRNA Plasmid (h) - sc-63100-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TAPP1 shRNA (h) Lentiviral Particles - sc-63100-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU137611 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16946 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16946 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11476 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11476

PLEKHA1 siRNA (Human) - CRJ1771 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLEKHA1 (NM_021622.4) - SHH377452 from Creative biogene

Category siRNA
Species Reactivities Human

PLEKHA1 shRNA Plasmid (Human) - CHJ1771 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLEKHA1 miRNA 3'UTR clone - MiUTR4H-TG06758 from Creative biogene

Species Reactivities Human
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