Gene Symbol |
SPINK6
|
Entrez Gene |
404203
|
Alt Symbol |
BUSI2, UNQ844
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
serine peptidase inhibitor, Kazal type 6
|
Other Description |
acrosin inhibitor|kallikrein inhibitor|protease inhibitor H|serine protease inhibitor Kazal-type 6
|
Swissprots |
Q6UWN8 E0X656 Q8N5P0
|
Accessions |
EAW61813 EAW61814 Q6UWN8 AY358716 AAQ89078 BC032003 AAH32003 BE122852 GQ504704 ADM46526 GQ504705 ADM46527 NM_001195290 NP_001182219 NM_205841 NP_995313
|
Function |
Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8. {ECO:0000269|PubMed:20667819, ECO:0000269|PubMed:21439340}.
|
Subcellular Location |
Secreted {ECO:0000250|UniProtKB:Q8BT20}.
|