Gene Symbol | SPINK6 |
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Entrez Gene | 404203 |
Alt Symbol | BUSI2, UNQ844 |
Species | Human |
Gene Type | protein-coding |
Description | serine peptidase inhibitor, Kazal type 6 |
Other Description | acrosin inhibitor|kallikrein inhibitor|protease inhibitor H|serine protease inhibitor Kazal-type 6 |
Swissprots | Q6UWN8 E0X656 Q8N5P0 |
Accessions | EAW61813 EAW61814 Q6UWN8 AY358716 AAQ89078 BC032003 AAH32003 BE122852 GQ504704 ADM46526 GQ504705 ADM46527 NM_001195290 NP_001182219 NM_205841 NP_995313 |
Function | Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8. {ECO:0000269|PubMed:20667819, ECO:0000269|PubMed:21439340}. |
Subcellular Location | Secreted {ECO:0000250|UniProtKB:Q8BT20}. |
SPINK6 CRISPR/Cas9 KO Plasmid (h) - sc-418110 from Santa Cruz Biotechnology
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SPINK6 HDR Plasmid (h) - sc-418110-HDR from Santa Cruz Biotechnology
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SPINK6 Double Nickase Plasmid (h) - sc-418110-NIC from Santa Cruz Biotechnology
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SPINK6 Double Nickase Plasmid (h2) - sc-418110-NIC-2 from Santa Cruz Biotechnology
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SPINK6 CRISPR Activation Plasmid (h) - sc-418110-ACT from Santa Cruz Biotechnology
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SPINK6 CRISPR Activation Plasmid (h2) - sc-418110-ACT-2 from Santa Cruz Biotechnology
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SPINK6 Lentiviral Activation Particles (h) - sc-418110-LAC from Santa Cruz Biotechnology
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SPINK6 Lentiviral Activation Particles (h2) - sc-418110-LAC-2 from Santa Cruz Biotechnology
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SPINK6 siRNA (h) - sc-91966 from Santa Cruz Biotechnology
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SPINK6 shRNA Plasmid (h) - sc-91966-SH from Santa Cruz Biotechnology
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SPINK6 shRNA (h) Lentiviral Particles - sc-91966-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN20484 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20484 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01148 from Sigma-Aldrich
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SPINK6 siRNA (Human) - CRJ8183 from Cohesion Biosciences
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SPINK6 - MBS8224703 from MyBioSource
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shRNA set against Human SPINK6 (NM_205841.3) - SHH416812 from Creative biogene
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Human SPINK6 siRNA - orb278684 from Biorbyt
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SPINK6 shRNA Plasmid (Human) - CHJ8183 from Cohesion Biosciences
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SPINK6 miRNA 3'UTR clone - MiUTR3H-15187 from Creative biogene
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