| Gene Symbol |
BDKRB2
|
| Entrez Gene |
624
|
| Alt Symbol |
B2R, BK-2, BK2, BKR2, BRB2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
bradykinin receptor B2
|
| Other Description |
B2 bradykinin receptor|BK-2 receptor
|
| Swissprots |
P30411
|
| Accessions |
AAB23467 AAB25765 AAK56376 EAW81629 P30411 AI095360 AK299316 BAG61326 AK311049 AY275465 AAP32297 BC074894 AAH74894 BC074895 AAH74895 CR749338 CAH18192 DA096163 DC422332 M88714 AAB02793 U35875 X69680 CAA49360 X86164 CAA60108 X86165 CAA60109 NM_000623 NP_000614
|
| Function |
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Ubiquitous. Widespread in normal smooth muscle tissue and neurons. {ECO:0000269|PubMed:7835885}.
|
| Top Pathways |
Chagas disease (American trypanosomiasis), Sphingolipid signaling pathway, cGMP-PKG signaling pathway, Inflammatory mediator regulation of TRP channels, Endocrine and other factor-regulated calcium reabsorption
|