Gene Symbol | BDKRB2 |
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Entrez Gene | 624 |
Alt Symbol | B2R, BK-2, BK2, BKR2, BRB2 |
Species | Human |
Gene Type | protein-coding |
Description | bradykinin receptor B2 |
Other Description | B2 bradykinin receptor|BK-2 receptor |
Swissprots | P30411 |
Accessions | AAB23467 AAB25765 AAK56376 EAW81629 P30411 AI095360 AK299316 BAG61326 AK311049 AY275465 AAP32297 BC074894 AAH74894 BC074895 AAH74895 CR749338 CAH18192 DA096163 DC422332 M88714 AAB02793 U35875 X69680 CAA49360 X86164 CAA60108 X86165 CAA60109 NM_000623 NP_000614 |
Function | Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Ubiquitous. Widespread in normal smooth muscle tissue and neurons. {ECO:0000269|PubMed:7835885}. |
Top Pathways | Chagas disease (American trypanosomiasis), Sphingolipid signaling pathway, cGMP-PKG signaling pathway, Inflammatory mediator regulation of TRP channels, Endocrine and other factor-regulated calcium reabsorption |
bradykinin B2 R CRISPR/Cas9 KO Plasmid (h) - sc-401771 from Santa Cruz Biotechnology
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bradykinin B2 R HDR Plasmid (h) - sc-401771-HDR from Santa Cruz Biotechnology
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bradykinin B2 R Double Nickase Plasmid (h) - sc-401771-NIC from Santa Cruz Biotechnology
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bradykinin B2 R Double Nickase Plasmid (h2) - sc-401771-NIC-2 from Santa Cruz Biotechnology
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bradykinin B2 R CRISPR Activation Plasmid (h) - sc-401771-ACT from Santa Cruz Biotechnology
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bradykinin B2 R CRISPR Activation Plasmid (h2) - sc-401771-ACT-2 from Santa Cruz Biotechnology
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bradykinin B2 R Lentiviral Activation Particles (h) - sc-401771-LAC from Santa Cruz Biotechnology
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bradykinin B2 R Lentiviral Activation Particles (h2) - sc-401771-LAC-2 from Santa Cruz Biotechnology
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bradykinin B2 R siRNA (h) - sc-29822 from Santa Cruz Biotechnology
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bradykinin B2 R shRNA Plasmid (h) - sc-29822-SH from Santa Cruz Biotechnology
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bradykinin B2 R shRNA (h) Lentiviral Particles - sc-29822-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU035001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3938 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3938 from Sigma-Aldrich
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BDKRB2 siRNA (Human) - CRH0424 from Cohesion Biosciences
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BDKRB2 - MBS8222577 from MyBioSource
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shRNA set against Human BDKRB2 (NM_000623.3) - SHH246226 from Creative biogene
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shRNA set against Human BDKRB2(NM_000623.3) - SHG098569 from Creative biogene
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Human BDKRB2 siRNA - orb260926 from Biorbyt
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BDKRB2 shRNA Plasmid (Human) - CHH0424 from Cohesion Biosciences
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BDKRB2 miRNA 3'UTR clone - MiUTR1H-00864 from Creative biogene
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