| Gene Symbol |
VPS45
|
| Entrez Gene |
11311
|
| Alt Symbol |
H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuolar protein sorting 45 homolog (S. cerevisiae)
|
| Other Description |
hlVps45|leucocyte vacuolar protein sorting 45|vacuolar protein sorting 45A|vacuolar protein sorting-associated protein 45
|
| Swissprots |
Q15715 D3DUZ9 Q5T4P6 Q9NRW7 Q9Y4Z6 F5H8K1 Q53FR8
|
| Accessions |
CAI14265 CAI14266 EAW53584 EAW53585 Q9NRW7 AF165513 AAF86643 AJ133421 CAB40417 AK023170 BAB14443 AK223214 BAD96934 AK293555 BAH11533 AK295529 BAH12096 AK298786 BAH12870 AK298835 BAH12880 AK301994 BAH13603 AK307949 AY453586 AAS49034 BC012932 AAH12932 BC028382 AAH28382 BG176899 CR743023 DA122826 DA374440 JF432313 ADZ15530 U35246 AAC50931 XR_921733 XR_921734 XR_921735 NM_001279353 NP_001266282 NM_001279354 NP_001266283 NM_001279355 NP_001266284 NM_007259 NP_009190 NR_103998
|
| Function |
May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with Golgi/endosomal vesicles and the trans-Golgi network. {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver.
|
| Top Pathways |
Endocytosis
|
![Western Blot: VPS45 Overexpression Lysate (Adult Normal) [NBL1-17753] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VPS45.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7877_VPS45%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17753-img0002.jpg)