CEP164

Gene Symbol CEP164
Entrez Gene 22897
Alt Symbol NPHP15
Species Human
Gene Type protein-coding
Description centrosomal protein 164kDa
Other Description centrosomal protein of 164 kDa
Swissprots Q7Z2X9 Q9UPV0 Q9UFJ6 Q9NVS0 Q6PKH9
Accessions CCQ43474 EAW67318 EAW67319 EAW67320 EAW67321 Q9UPV0 AB028975 BAA83004 AK001412 BAA91677 AK125995 BAC86384 AK302991 BAH13870 AK303067 BAG64184 AL117632 CAB56023 AL137265 CAB70664 AL833532 BC000602 AAH00602 BC054015 AAH54015 BC152748 AAI52749 BC156876 AAI56877 BX647583 BX648682 XM_005271453 XP_005271510 XM_005271456 XP_005271513 XM_005271457 XP_005271514 XM_006718788 XP_006718851 XM_006718794 XP_006718857 XM_011542670 XP_011540972 XM_011542671 XP_011540973 XM_011542672 XP_011540974 XM_011542673 XP_011540975 XM_011542674 XP_011540976 XM_011542675 XP_011540977 XM_011542676 XP_011540978 XM_011542677 XP_011540979 XM_011542678 XP_011540980 XM_011542679 XP_011540981 XM_011542680 XP_011540982 XM_011542681 XP_011540983 XM_011542682 XP_011540984 XM_011542683 XP_011540985 XM_011542685 XP_011540987 XM_011542686 XP_011540988 XM_011542687 XP_011540989 XM_011542688 XP_011540990 XM_011542689 XP_011540991 XM_011542690 XP_011540992 XR_428971 XR_947808 XR_947809 XR_947810 XR_947811 NM_001271933 NP_001258862 NM_014956 NP_055771
Function Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA, CHEK2 and CHEK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHEK1. {ECO:0000269|PubMed:17954613, ECO:0000269|PubMed:18283122, ECO:0000269|PubMed:23348840}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus. Note=Localizes specifically to very distally located appendage structures on the mature centriole from which initiate PC formation. Persisted at centrioles throughout mitosis. Expressed in chromatin-enriched nuclear fraction of HeLa cells. In response to DNA damage, it translocates to nuclear foci that contain the DNA damage response proteins KAT5/TIP60 and CHEK1.
Tissue Specificity Expressed in several cell lines. {ECO:0000269|PubMed:17954613}.

CEP164 (N-14) - sc-240226 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CEP164 antibody - ab106372 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CEP164 antibody (ab106372) at 1 µg/mlLane 2 : Anti-CEP164 antibody (ab106372) at 2 µg/mlLane 1 : Rat heart tissue lysate Lane 2 : Rat heart tissue lysate Lysates/proteins at 15 µg per lane.

Anti-CEP164 Antibody (N-Terminus) IHC-plus™ - LS-B4601 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CEP164 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4601 concentration 5 ug/ml.

Anti-CEP164 Antibody (aa246-274, AP) - LS-C254540 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274, Biotin) - LS-C254542 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274, APC) - LS-C254541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274, FITC) - LS-C254545 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274, PE) - LS-C254549 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274, Azide-free, HRP) - LS-C254548 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274) - LS-C320309 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CEP164 Antibody (aa246-274) - LS-C168643 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CE164 Antibody western blot of A549 cell line lysates (35 ug/lane). The CE164 antibody detected the CE164 protein (arrow).

CEP164 Antibody - 45330002 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

CEP164 Antibody - NBP1-81445 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CEP164 Antibody [NBP1-81445] - Staining of human cell line U-2 OS shows localization to centrosome.

CEP164 Antibody - NBP1-77006 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CEP164 Antibody [NBP1-77006] - Rat heart tissue lysate with CEP164 antibody at (A) 1 and (B) 2 ug/ml.

Anti-CEP164 antibody produced in rabbit - HPA037606 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CEP164: <B>Cat. No. HPA037606</B>: Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Anti-CEP164 antibody produced in rabbit - HPA037605 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CEP164: <B>Cat. No. HPA037605</B>: Immunohistochemical staining of human stomach shows strong membranous and cytoplasmic positivity in glandular cells.

Monoclonal Anti-CEP164 antibody produced in mouse - SAB2702133 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Mouse
<B>Immunoblotting</B><BR/>Monoclonal Anti-CEP164: <B>Cat. No. SAB2702133</B>: Western blot analysis of CEP164 in extracts from 30 μg of whole cell HeLa 5% SDS-PAGE at a 1:1,000 dilution.

Anti-CEP164 antibody produced in rabbit - SAB3500022 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CEP164: <B>Cat. No. SAB3500022</B>: CEP164 in mouse heart tissue with CEP164 antibody at 5 μg/mL.

ANTI-CE164(N-TERMINAL) antibody produced in rabbit - SAB1306105 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CE164 (N-term): <B>Cat. No. SAB1306105</B>: CE164 Antibody (N-term) western blot analysis in A549 cell line lysates (35 μg/lane).

CEP164 Antibody - N-terminal region (OAAB01001) - OAAB01001 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CE164-Antibody-N-term - AP10981a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
CE164 Antibody (N-term) (Cat. #AP10981a) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

CEP164 antibody [13] - GTX70094 from GeneTex

Prices $319.00
Sizes 100 μl
Host Mouse
Clonality Monoclonal
Clone 13
Anti-Cep 164 antibody [13] used in Western blot. GTX70094

CEP164 antibody [17] - GTX70096 from GeneTex

Prices $319.00
Sizes 100 μl
Host Mouse
Clonality Monoclonal
Clone 17
Anti-Cep 164 antibody [17] used in Western blot. GTX70096

CEP164 antibody - GTX85298 from GeneTex

Prices $299.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-CEP164 antibody used in Immunohistochemistry. GTX85298

CEP164 antibody - orb75166 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat heart tissue lysate at (A) 1 and (B) 2 ug/mL using CEP164 antibody
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