| Gene Symbol |
HYAL4
|
| Entrez Gene |
23553
|
| Alt Symbol |
CSHY
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hyaluronoglucosaminidase 4
|
| Other Description |
chondroitin sulfate endo-beta-N-acetylgalactosaminidase|chondroitin sulfate hydrolase|hyal-4|hyaluronidase 4|hyaluronidase-4|hyaluronoglucosaminidase-4
|
| Swissprots |
Q2M3T9 D0VXG1 Q9Y6T9 Q9UL99
|
| Accessions |
AAD43186 EAL24331 EAW83603 Q2M3T9 AB470346 BAI49593 AF009010 AAC98883 BC104788 AAI04789 BC104790 AAI04791 BC143654 BF085228 BG013757 XM_011515990 XP_011514292 XM_011515991 XP_011514293 XM_011515992 XP_011514294 XR_927425 NM_012269 NP_036401
|
| Function |
Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitin sulfate hydrolase activity, The best substrate being the galactosaminidic linkage in the sequence of a trisulfated tetrasaccharide. {ECO:0000269|PubMed:16104017, ECO:0000269|PubMed:19889881}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Detected in placenta and skeletal muscle. {ECO:0000269|PubMed:10493834}.
|
| Top Pathways |
Glycosaminoglycan degradation
|