Fgf2
| Gene Symbol | Fgf2 |
|---|---|
| Entrez Gene | 14173 |
| Alt Symbol | Fgf-2, Fgfb, bFGF |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | fibroblast growth factor 2 |
| Other Description | HBGF-2|basic fibroblast growth factor|heparin-binding growth factor 2 |
| Swissprots | P15655 |
| Accessions | AAK53871 AAP92384 AAP92385 EDL35104 EDL35105 EDL35106 EDL35107 EDL35108 P15655 AF065903 AAC17503 AF065904 AAC17504 AF065905 AAC17505 AY027548 AY027549 AY027550 AY027551 AAK52308 AY027557 AAK52309 AY027558 AAK52310 AY027559 BC156158 AAI56159 BC156994 AAI56995 BY730691 CJ098597 M30644 AAA37621 XM_006502586 XP_006502649 XM_006535398 XP_006535461 XM_006535399 XP_006535462 NM_008006 NP_032032 |
| Function | Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted {ECO:0000250}. Nucleus {ECO:0000250}. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity). {ECO:0000250}. |
| Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Rap1 signaling pathway |
bFGF Polyclonal Antibody - bs-0217R from Bioss
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bFGF Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0217R-A350 from Bioss
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bFGF Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0217R-A488 from Bioss
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bFGF Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0217R-A555 from Bioss
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bFGF Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0217R-A647 from Bioss
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bFGF Polyclonal Antibody, Cy3 Conjugated - bs-0217R-Cy3 from Bioss
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bFGF Polyclonal Antibody, Cy5 Conjugated - bs-0217R-Cy5 from Bioss
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bFGF Polyclonal Antibody, Cy5.5 Conjugated - bs-0217R-Cy5.5 from Bioss
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bFGF Polyclonal Antibody, Cy7 Conjugated - bs-0217R-Cy7 from Bioss
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bFGF Polyclonal Antibody, FITC Conjugated - bs-0217R-FITC from Bioss
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bFGF Polyclonal Antibody, Biotin Conjugated - bs-0217R-Biotin from Bioss
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bFGF Polyclonal Antibody, HRP Conjugated - bs-0217R-HRP from Bioss
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FGF2 antibody - orb66832 from Biorbyt
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FGF2 Antibody (OABF00102) - OABF00102 from Aviva Systems Biology
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HBEGF antibody - 70R-15470 from Fitzgerald
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FGF-2 antibody - orb97693 from Biorbyt
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HBEGF antibody (HRP) - 60R-2229 from Fitzgerald
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HBEGF antibody (biotin) - 60R-2227 from Fitzgerald
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HBEGF antibody (FITC) - 60R-2228 from Fitzgerald
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FGF2 antibody - 70R-12253 from Fitzgerald
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FGF 2 Antibody - TGB-376 from Reagent Proteins
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Fibroblast Growth Factor basic (mouse) Recombinant Protein - RP-8626 from Thermo Fisher Scientific
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Polyclonal Antibody to Fibroblast Growth Factor 2, Basic (FGF2) - PAA551Mu01 from Cloud-clone
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Polyclonal Antibody to Fibroblast Growth Factor 2, Basic (FGF2) - PAA551Mu02 from Cloud-clone
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Rabbit Anti-bFGF Polyclonal Antibody, PE Conjugated - bs-0217R-PE from Bioss
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