PPP2R1A

Gene Symbol PPP2R1A
Entrez Gene 5518
Alt Symbol PP2A-Aalpha, PP2AAALPHA, PR65A
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit A, alpha
Other Description PP2A subunit A isoform PR65-alpha|PP2A subunit A isoform R1-alpha|medium tumor antigen-associated 61 KDA protein|protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform|serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform|serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Swissprots Q6ICQ3 Q13773 Q96DH3 P30153
Accessions AAA35531 EAW72066 P30153 AK090488 BAG52168 AK091387 BAC03652 AK130000 AK290593 BAF83282 AK291932 BAF84621 AK293174 BAG56718 AK293493 BAG56980 AK299012 BAG61093 AK303934 BAG64862 AK307743 AK315700 BAG38062 AU128747 BC001537 AAH01537 BC026733 BT008074 AAP36766 CA426613 CR450340 CAG29336 DB246691 DC398468 DQ892756 ABM83682 DQ896000 ABM86978 J02902 AAA36399 NM_014225 NP_055040 NR_033500
Function The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis. {ECO:0000269|PubMed:16580887}.
Subcellular Location Cytoplasm {ECO:0000250}. Chromosome, centromere {ECO:0000269|PubMed:16580887}. Note=Centromeric localization requires the presence of BUB1.
Top Pathways Sphingolipid signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway, Hippo signaling pathway, TGF-beta signaling pathway

PP2A A Subunit (6G3) Rat mAb - 2260 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rat
Clonality Monoclonal
Clone 6G3
Western blot analysis of extracts from HeLa, NIH/3T3, C6 and COS cells, using PP2A A Subunit (6G3) Rat mAb.

PP2A A Subunit (81G5) Rabbit mAb - 2041 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 81G5
Western blot analysis of extracts from various cell lines using PP2A A Subunit (81G5) Rabbit mAb.

PP2A A Subunit Antibody - 2039 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa, NIH/3T3, C6 and COS cells, using PP2A A Subunit Antibody.

PP2A A Subunit (4G7) Mouse mAb - 4955 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone 4G7
Western blot analysis of extracts from PL45, L929, C6 and COS cells using PP2A A Subunit (4G7) Mouse mAb.

PP2A-Aα (6F9) - sc-56953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
PP2A-Aα (6F9): sc-56953. Western blot analysis of PP2A-Aα expression in C3H/10T1/2 (A), 3T3-L1 (B) and P19 (C) whole cell lysates.

PP2A-Aα (6G3) - sc-56954 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
PP2A-Aα (6G3): sc-56954. Western blot analysis of PP2A-Aα expression in H4 (A), NIH/3T3 (B), SW480 (C), T-47D (D), KNRK (E) and Jurkat (F) whole cell lysates.

PP2A-Aα (5H4) - sc-56952 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

PP2A-Aα (C-20) - sc-6112 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PP2A-Aα/β (C-20): sc-6112. Western blot analysis of PP2A-Aα/β expression in H4 (A) and NIH/3T3 (B) whole cell lysates.

PP2A-Aα/β (B-1) - sc-374264 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PP2A-Aα/β (B-1): sc-374264. Western blot analysis of PP2A-Aα/β expression in Jurkat (A) and Ramos (B) whole cell lysates.

PP2A-Aα/β (A-5) - sc-74580 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PP2A-Aα/β (A-5): sc-74580. Western blot analysis of PP2A-Aα/β expression in KNRK (A), H4 (B), NIH/3T3 (C) and Ramos (D) whole cell lysates.

PP2A-Aα/β (4C10) - sc-81604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PP2A-Aa/b (4C10): sc-81604. Western blot analysis of PP2A-Aa/b expression in Hela (A) and NIH/3T3 (B) whole cell lysates. Kindly provided by Drs. Ingrid Mudrak and Egon Ogris.

PP2A-Aα/β (4G7) - sc-13600 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PP2A-A (4G7): sc-13600. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tumor showing cytoplasmic localization.

PP2A-Aα/β (H-2) - sc-373738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PP2A-Aα/β (H-2): sc-373738. Western blot analysis of PP2A-Aα/β expression in Jurkat (A) and Ramos (B) whole cell lysates.

PP2A-Aα/β (H-300) - sc-15355 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PP2A-Aα/β (H-300): sc-15355. Western blot analysis of PP2A-Aα/β expression in KNRK whole cell lysate.

PP2A-Aα/β (H-11) - sc-74579 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PP2A-Aα/β (H-11): sc-74579. Western blot analysis of PP2A-Aα/β expression in KNRK (A), H4 (B), NIH/3T3 (C) and Ramos (D) whole cell lysates.

PP2A-Aα/β (3J18) - sc-80989 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-PPP2R1A antibody - ab88073 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-PPP2R1A antibody (ab88073) at 1 µg/ml + Jurkat cell lysate at 50 µgSecondaryGoat anti-mouse IgG at 1/5000 dilution

Anti-PPP2R1A antibody [4E6] - ab129289 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4E6
ab129289, at 5&microg/ml, staining PPP2R1A in Formalin-fixed, Paraffin-embedded Human liver tissue by Immunohistochemistry.

Anti-PPP2R1A antibody [5H4] - ab24730 from Abcam

Prices $370.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 5H4

Anti-PPP2R1A antibody - Aminoterminal end - ab76697 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PPP2R1A antibody - Aminoterminal end (ab76697) at 1/60 dilutionLane 1 : Jurkat cell line lysateLane 2 : T47D cell line lysateLane 3 : HepG2 cell line lysateLysates/proteins at 35 µg per lane.

Anti-PPP2R1A Antibody (aa6-19) - LS-C26215 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-PPP2R1A Antibody (aa7-19) - LS-C26538 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-PPP2R1A Antibody (aa1-11) - LS-C38586 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP2R1A Antibody (C-Terminus) - LS-C91581 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP2R1A Antibody (aa454-481, APC) - LS-C266941 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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