PPP2R1A

Gene Symbol PPP2R1A
Entrez Gene 5518
Alt Symbol PP2A-Aalpha, PP2AAALPHA, PR65A
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit A, alpha
Other Description PP2A subunit A isoform PR65-alpha|PP2A subunit A isoform R1-alpha|medium tumor antigen-associated 61 KDA protein|protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform|serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform|serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Swissprots Q6ICQ3 Q13773 Q96DH3 P30153
Accessions AAA35531 EAW72066 P30153 AK090488 BAG52168 AK091387 BAC03652 AK130000 AK290593 BAF83282 AK291932 BAF84621 AK293174 BAG56718 AK293493 BAG56980 AK299012 BAG61093 AK303934 BAG64862 AK307743 AK315700 BAG38062 AU128747 BC001537 AAH01537 BC026733 BT008074 AAP36766 CA426613 CR450340 CAG29336 DB246691 DC398468 DQ892756 ABM83682 DQ896000 ABM86978 J02902 AAA36399 NM_014225 NP_055040 NR_033500
Function The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis. {ECO:0000269|PubMed:16580887}.
Subcellular Location Cytoplasm {ECO:0000250}. Chromosome, centromere {ECO:0000269|PubMed:16580887}. Note=Centromeric localization requires the presence of BUB1.
Top Pathways Sphingolipid signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway, Hippo signaling pathway, TGF-beta signaling pathway

PP2A-Aα CRISPR/Cas9 KO Plasmid (h) - sc-400876 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα HDR Plasmid (h) - sc-400876-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα Double Nickase Plasmid (h) - sc-400876-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα Double Nickase Plasmid (h2) - sc-400876-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα CRISPR Activation Plasmid (h) - sc-400876-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα CRISPR Activation Plasmid (h2) - sc-400876-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα Lentiviral Activation Particles (h) - sc-400876-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα Lentiviral Activation Particles (h2) - sc-400876-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PP2A-Aα siRNA (h) - sc-44033 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PP2A-Aα shRNA Plasmid (h) - sc-44033-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PP2A-Aα shRNA (h) Lentiviral Particles - sc-44033-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPP2R1A RNAi - H00005518-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU071351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0609 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0607 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0608 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN1475 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1475 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PPP2R1A siRNA (Human) - CRH3697 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PPP2R1A (NM_014225.5) - SHH381360 from Creative biogene

Category siRNA
Species Reactivities Human

Human PPP2R1A siRNA - orb264199 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPP2R1A shRNA Plasmid (Human) - CHH3697 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PPP2R1A miRNA 3'UTR clone - MiUTR3H-08100 from Creative biogene

Species Reactivities Human
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