SLC17A4

Gene Symbol SLC17A4
Entrez Gene 10050
Alt Symbol KAIA2138
Species Human
Gene Type protein-coding
Description solute carrier family 17, member 4
Other Description Na/PO4 cotransporter|probable small intestine urate exporter|putative small intestine sodium-dependent phosphate transport protein|solute carrier family 17 (sodium phosphate), member 4
Swissprots E7EU17 E7EPE8 Q32MB8 Q9Y2C5 B4DDV9 Q32MB7
Accessions EAW55492 EAW55493 Q9Y2C5 AB020527 BAA76663 AK024903 AK293354 BAG56870 AK308500 BC109207 AAI09208 BC109208 AAI09209 XM_011514206 XP_011512508 XM_011514207 XP_011512509 XM_011514208 XP_011512510 XM_011514209 XP_011512511 XM_011514210 XP_011512512 XM_011514211 XP_011512513 XM_011514212 XP_011512514 XM_011514213 XP_011512515 XM_011514214 XP_011512516 XM_011514215 XP_011512517 XM_011514216 XP_011512518 XM_011514217 XP_011512519 XM_011514218 XP_011512520 XM_011514219 XP_011512521 XR_925996 XR_925997 XR_925998 XR_925999 NM_001286121 NP_001273050 NM_005495 NP_005486
Function Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro). {ECO:0000269|PubMed:22460716}.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:22460716}; Multi-pass membrane protein {ECO:0000269|PubMed:22460716}. Cell membrane {ECO:0000269|PubMed:22460716}; Multi-pass membrane protein {ECO:0000269|PubMed:22460716}. Note=Apical in the intestinal brush border.
Tissue Specificity Abundantly expressed in pancreas, liver, colon and small intestine, less in kidney. Not detected in the adrenal glands, brain, placenta, heart, testis, skeletal muscle, and lungs. {ECO:0000269|PubMed:10319585, ECO:0000269|PubMed:22460716}.

SLC17A4 CRISPR/Cas9 KO Plasmid (h) - sc-408667 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 HDR Plasmid (h) - sc-408667-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 Double Nickase Plasmid (h) - sc-408667-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 Double Nickase Plasmid (h2) - sc-408667-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 CRISPR Activation Plasmid (h) - sc-408667-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 CRISPR Activation Plasmid (h2) - sc-408667-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 Lentiviral Activation Particles (h) - sc-408667-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 Lentiviral Activation Particles (h2) - sc-408667-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLC17A4 siRNA (h) - sc-95575 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC17A4 shRNA Plasmid (h) - sc-95575-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC17A4 shRNA (h) Lentiviral Particles - sc-95575-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC17A4 RNAi - H00010050-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN19437 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19437 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07863 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07863

SLC17A4 siRNA (Human) - CRH6766 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC17A4 - MBS8235107 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SLC17A4 siRNA - orb267268 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC17A4 shRNA Plasmid (Human) - CHH6766 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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