CDK11A

Gene Symbol CDK11A
Entrez Gene 728642
Alt Symbol CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA
Species Human
Gene Type protein-coding
Description cyclin-dependent kinase 11A
Other Description PITSLRE B|PITSLRE protein kinase beta|PITSLRE serine/threonine-protein kinase CDC2L2|cell division cycle 2-like 2 (PITSLRE proteins)|cell division cycle 2-like protein kinase 2|cell division protein kinase 11A|galactosyltransferase-associated protein kinase p58/GTA
Swissprots Q12821 Q9UQ88 Q12853 Q9UP53 Q9UEI2 Q9UBC4 Q2TAJ0 Q9UQ86 O95227 Q9UP54 Q9UBI3 Q12854 Q5QPR1 O95228 O96012 Q9UQ87 Q9UEI1 Q9UP56 Q9UP55 Q5QPR2 Q9UQ89 Q5QPR0
Accessions AAC95297 AAC95298 AAC95299 AAC95300 AAC95301 AAC95302 AAC95303 AAC95304 EAW56161 EAW56162 EAW56163 EAW56164 EAW56165 EAW56166 EAW56167 EAW56168 Q9UQ88 AF067518 AAC72083 AF067519 AAC72084 AF067520 AAC72085 AF067521 AAC72086 AF067522 AAC72087 AF067523 AAC72088 AF067524 AAC72089 AF067526 AAC72091 AF067527 AAC72092 AF067528 AAC72093 AF067529 AAC72094 AK301495 BAG63006 AK303446 BAG64491 AK303451 BAG64496 AL043340 BC014464 AAH14464 BC028187 AAH28187 BC073855 BC094827 AAH94827 BC110905 AAI10906 DC388505 U04819 AAA19585 U07704 AAA19594 U07705 AAA19595 NM_024011 NP_076916 NM_033529 NP_277071 NM_033527 NM_033532 NM_033534
Function Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression. {ECO:0000269|PubMed:12501247, ECO:0000269|PubMed:12624090}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. {ECO:0000269|PubMed:8195233, ECO:0000269|PubMed:9750192}.

PITSLRE B CRISPR/Cas9 KO Plasmid (h) - sc-402477 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B HDR Plasmid (h) - sc-402477-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B Double Nickase Plasmid (h) - sc-402477-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B Double Nickase Plasmid (h2) - sc-402477-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B CRISPR Activation Plasmid (h) - sc-402477-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B CRISPR Activation Plasmid (h2) - sc-402477-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B Lentiviral Activation Particles (h) - sc-402477-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B Lentiviral Activation Particles (h2) - sc-402477-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PITSLRE B siRNA (h) - sc-106416 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PITSLRE B shRNA Plasmid (h) - sc-106416-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PITSLRE B shRNA (h) Lentiviral Particles - sc-106416-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU114721 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5836 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5836 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CDK11A siRNA (Human) - CRJ8685 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDK11A - MBS8219160 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CDK11A (NM_024011.2) - SHH260481 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CDC2L2(NM_024011.2) - SHG161137 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CDC2L2(NM_033529.2) - SHG161191 from Creative biogene

Category siRNA
Species Reactivities Human

Human CDK11A siRNA - orb279186 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDK11A shRNA Plasmid (Human) - CHJ8685 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CDK11A miRNA 3'UTR clone - MiUTR1H-01946 from Creative biogene

Species Reactivities Human

CDK11A miRNA 3'UTR clone - MiUTR1H-01947 from Creative biogene

Species Reactivities Human
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