CDK11A

Gene Symbol	CDK11A
Entrez Gene	728642
Alt Symbol	CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase 11A
Other Description	PITSLRE B\|PITSLRE protein kinase beta\|PITSLRE serine/threonine-protein kinase CDC2L2\|cell division cycle 2-like 2 (PITSLRE proteins)\|cell division cycle 2-like protein kinase 2\|cell division protein kinase 11A\|galactosyltransferase-associated protein kinase p58/GTA
Swissprots	Q12821 Q9UQ88 Q12853 Q9UP53 Q9UEI2 Q9UBC4 Q2TAJ0 Q9UQ86 O95227 Q9UP54 Q9UBI3 Q12854 Q5QPR1 O95228 O96012 Q9UQ87 Q9UEI1 Q9UP56 Q9UP55 Q5QPR2 Q9UQ89 Q5QPR0
Accessions	AAC95297 AAC95298 AAC95299 AAC95300 AAC95301 AAC95302 AAC95303 AAC95304 EAW56161 EAW56162 EAW56163 EAW56164 EAW56165 EAW56166 EAW56167 EAW56168 Q9UQ88 AF067518 AAC72083 AF067519 AAC72084 AF067520 AAC72085 AF067521 AAC72086 AF067522 AAC72087 AF067523 AAC72088 AF067524 AAC72089 AF067526 AAC72091 AF067527 AAC72092 AF067528 AAC72093 AF067529 AAC72094 AK301495 BAG63006 AK303446 BAG64491 AK303451 BAG64496 AL043340 BC014464 AAH14464 BC028187 AAH28187 BC073855 BC094827 AAH94827 BC110905 AAI10906 DC388505 U04819 AAA19585 U07704 AAA19594 U07705 AAA19595 NM_024011 NP_076916 NM_033529 NP_277071 NM_033527 NM_033532 NM_033534
Function	Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression. {ECO:0000269\|PubMed:12501247, ECO:0000269\|PubMed:12624090}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Expressed ubiquitously. Some evidence of isoform-specific tissue distribution. {ECO:0000269\|PubMed:8195233, ECO:0000269\|PubMed:9750192}.

Anti-CDK11 / CDC2L2 antibody - ab19393 from Abcam

Prices	$380.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach carcinoma tissue labelling CDK11 / CDC2L2 with ab19393 at 1/1000 (1µg/ml). Detection: DAB.

Anti-CDK11 / CDC2L2 antibody - ab128681 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11 / CDC2L2 antibody (ab128681) at 1 µg/ml + Human fetal brain lysate at 10 µgSecondaryGoat anti-Rabbit IgG HRPdeveloped using the ECL technique

Anti-CDK11 / CDC2L2 antibody (Biotin) - ab113266 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-CDK11 / CDC2L2 antibody (Biotin) (ab113266) at 1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µg

Anti-CDK11A / CDC2L2 Antibody (C-Terminus) - LS-C78855 from LifeSpan Bioscience

Prices	$545.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11A / CDC2L2 Antibody (aa50-100) - LS-C78854 from LifeSpan Bioscience

Prices	$545.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11A / CDC2L2 Antibody (aa50-100) - LS-C292254 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11A / CDC2L2 Antibody (aa681-780) - LS-C306860 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-CDK11A / CDC2L2 Antibody (aa696-745) - LS-C151459 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

CDK11A / CDC2L2 antibody Western Blot of Fetal Brain.

Anti-CDK11A / CDC2L2 Antibody (C-Terminus, Biotin) - LS-C287216 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human CDK11 by Western Blot. Samples: Whole cell lysate from HeLa (50 and 15 ug). Antibody: Affinity purified, biotin-conjugated, rabbit anti-CDK11 antibody used at 1.0 ug/ml. Detection: Streptavidin-HRP and chemiluminescence with an exposure time of 3 minutes.

Anti-CDK11A / CDC2L2 Antibody (FITC) - LS-C211751 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Cyclin-dependent kinase 11A antibody at 2 ug/ml + 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 87 kDa. Observed band size: 87 kDa.

Anti-CDK11A / CDC2L2 Antibody (HRP) - LS-C211750 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11A / CDC2L2 Antibody - LS-C211746 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11A / CDC2L2 Antibody (Biotin) - LS-C211752 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CDK11A / CDC2L2 Antibody (aa730-780) - LS-C56915 from LifeSpan Bioscience

Prices	$345.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Detection of human CDK11 in whole cell lysates (WCL) of HeLa cells by Western blotting with Rabbit anti-Human CDK11 (LS-C56915) and by immunoprecipitation with LS-C56915. the immunoprecipitate was resolved on a 4-20% gel , subsequently Coomassie stained and the CDK11 band was confirmed by mass spectrometry.

Anti-CDK11A / CDC2L2 Antibody (C-Terminus) - LS-C287217 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human CDK11 by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-CDK11 used at a dilution of 1:1000 (1 ug/ml).

Anti-CDK11A / CDC2L2 Antibody (C-Terminus) - LS-C286308 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human CDK11 by Immunohistochemistry. Sample: FFPE section of human stomach adenocarcinoma. Antibody: Affinity purified rabbit anti-CDK11 used at a dilution of 1:250. Detection: DAB.

CDC2L2 Antibody - NB100-496 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: CDC2L2 Antibody [NB100-496] - Analysis using the Biotin conjugate of NB100-496. Detection of HeLa (50 and 15 ug). Antibody used at 1.0 ug/ml.

CDC2L1 Antibody - NB100-495 from Novus Biologicals

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: CDC2L1 Antibody [NB100-495] - Whole cell lysate from HeLa (15 and 50 ug) and 293T cells (50 ug), stained with CDC2L1 Antibody diluted at 1 ug/ml.

CDC2L2 Antibody (1A9) - H00728642-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1A9

CDC2L2 Antibody [Biotin] - NBP1-71798 from Novus Biologicals

Host	Rabbit
Clonality	Polyclonal

Western Blot: CDC2L2 Antibody [Biotin] [NBP1-71798] - Whole cell lysate from HeLa (50 and 15 ug). Antibody used at 1.0 ug/ml.

Anti-CDK11A antibody produced in rabbit - HPA025061 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-CDK11A: <B>Cat. No. HPA025061</B>: Immunohistochemical staining of human duodenum shows strong nuclear positivity in glandular cells.

Monoclonal Anti-CDC2L2 antibody produced in mouse - SAB1402099 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1A9

<B>Immunofluorescence</B><BR/>Monoclonal Anti-CDC2L2, antibody produced in mouse, clone 1A9, purified immunoglobulin: <B>Cat. No. SAB1402099</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-CDK11A antibody produced in rabbit - SAB2107656 from Sigma-Aldrich

Prices	$341.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-CDK11A: <B>Cat. No. SAB2107656</B>: Western blot analysis of CDK11A in Fetal Brain with CDK11A (cyclin-dependent kinase 11A) antibody against the C terminal of CDK11A (50 μg) antibody at 1.0 μg/mL.

Anti-CDK11A/CDK11B antibody produced in rabbit - SAB4300838 from Sigma-Aldrich

Prices	$230.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

C4B Antibody (OASA01013) - OASA01013 from Aviva Systems Biology

Prices	$515.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	10-12

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