Gene Symbol | ALDH1A1 |
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Entrez Gene | 216 |
Alt Symbol | ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1 |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 1 family, member A1 |
Other Description | ALDH class 1|ALHDII|RALDH 1|acetaldehyde dehydrogenase 1|aldehyde dehydrogenase 1, soluble|aldehyde dehydrogenase, liver cytosolic|epididymis luminal protein 12|epididymis luminal protein 9|epididymis secretory sperm binding protein Li 53e|retinal dehydrogenase 1|retinaldehyde dehydrogenase 1 |
Swissprots | O00768 P00352 Q5SYR1 |
Accessions | AAA51692 AAD13925 AAD14823 AAP88039 CBH19844 EAW62543 EAW62544 P00352 AB209821 BAD93058 AF003341 AAC51652 AI074764 AK000118 AK026641 AK293176 BAG56719 AK302168 BAG63535 AY390731 AAR92229 BC001505 AAH01505 BG773210 BT006921 AAP35567 DC398835 DQ890669 ABM81595 DQ893850 ABM84776 EU668318 ACF94471 EU794589 ACJ13643 FJ224286 ACI45978 K03000 AAA51695 M26761 AAA35518 NM_000689 NP_000680 |
Function | Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Retinol metabolism |
ALDH1A1 CRISPR/Cas9 KO Plasmid (h) - sc-400782 from Santa Cruz Biotechnology
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ALDH1A1 HDR Plasmid (h) - sc-400782-HDR from Santa Cruz Biotechnology
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ALDH1A1 Double Nickase Plasmid (h) - sc-400782-NIC from Santa Cruz Biotechnology
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ALDH1A1 Double Nickase Plasmid (h2) - sc-400782-NIC-2 from Santa Cruz Biotechnology
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ALDH1A1 CRISPR Activation Plasmid (h) - sc-400782-ACT from Santa Cruz Biotechnology
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ALDH1A1 CRISPR Activation Plasmid (h2) - sc-400782-ACT-2 from Santa Cruz Biotechnology
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ALDH1A1 Lentiviral Activation Particles (h) - sc-400782-LAC from Santa Cruz Biotechnology
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ALDH1A1 Lentiviral Activation Particles (h2) - sc-400782-LAC-2 from Santa Cruz Biotechnology
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ALDH1A1 siRNA (h) - sc-41442 from Santa Cruz Biotechnology
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ALDH1A1 shRNA Plasmid (h) - sc-41442-SH from Santa Cruz Biotechnology
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ALDH1A1 shRNA (h) Lentiviral Particles - sc-41442-V from Santa Cruz Biotechnology
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Aldehyde Dehydrogenase 1-A1/ALDH1A1 RNAi - H00000216-R01 from Novus Biologicals
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MISSION® esiRNA - EHU028501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1779 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1779 from Sigma-Aldrich
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ALDH1A1 siRNA (Human) - CRH0151 from Cohesion Biosciences
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ALDH1A1 - MBS8201268 from MyBioSource
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ALDH1A1 CRISPR/Cas9 KO Plasmid (h2) - sc-400782-KO-2 from Santa Cruz Biotechnology
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ALDH1A1 HDR Plasmid (h2) - sc-400782-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ALDH1A1 (NM_000689.4) - SHH234790 from Creative biogene
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Human ALDH1A1 siRNA - orb260653 from Biorbyt
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ALDH1A1 shRNA Plasmid (Human) - CHH0151 from Cohesion Biosciences
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ALDH1A1 miRNA 3'UTR clone - MiUTR3H-00001 from Creative biogene
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